Gene: IGF1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 Biomarker disease BEFREE Our results suggest a role for IGF-1R and ErbB3 in driving chemotherapy resistance of ovarian cancer. 31728045 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 Biomarker disease BEFREE The IGF axis has been shown to play a significant role in carcinogenesis of several types of tissue, including ovarian cancer. 29922232 2018
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 Biomarker disease BEFREE In summary, IGF-1 activation represents an important mechanism of adaptive escape during anti-VEGF therapy in ovarian cancer. 22700681 2012
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 Biomarker disease BEFREE IGF/PI3K/AKT signaling pathway also plays certain roles in the program and regulation of human breast cancer and ovary cancer. 22094188 2012
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 Biomarker disease BEFREE The insulin-like growth factor 1 pathway is a potential therapeutic target for low-grade serous ovarian carcinoma. 21726895 2011
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 Biomarker disease BEFREE Both IGF-1R and Lewis(y) are associated with the occurrence and development of ovarian cancers. 22072919 2011
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 Biomarker disease BEFREE Our study reinforces the concept that IGF-1R is a good therapeutic target in ovarian cancer. 19699512 2009
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 GeneticVariation disease BEFREE Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk. 19858071 2009
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 Biomarker disease BEFREE However, the molecular mechanisms by which IGF-I contributes to ovarian cancer development remain to be elucidated. 17341442 2007
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 AlteredExpression disease BEFREE The study also suggests that both endocrine and paracrine/autocrine are involved in the regulation of IGF-I activity in ovarian cancer. 18236213 2007
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.100 Biomarker disease BEFREE IGF-1 and KCC colocalize in the surgical specimens of cervical cancer (n = 28) and ovarian cancer (n = 35), suggesting autocrine or paracrine IGF-1 stimulation of KCC production. 15262997 2004