Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 Biomarker disease BEFREE Our results demonstrate the successful isolation of intact and label-free exosomes, indicate that the amount of both total and EpCAM+ exosomes increases with HGSOC disease progression, and demonstrate the downstream internalization of isolated exosomes by OVCAR8 cells. 30191215 2018
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 Biomarker disease BEFREE Targeting EpCAM should be a promising approach to effectively extirpate the CSCs as the putative root of ovarian cancer. 28574829 2017
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 GeneticVariation disease BEFREE We screened the EpCAM-coding gene TACSTD1 for single nucleotide polymorphisms (SNPs), which could alter ovarian cancer risk, impact upon disease progression, or alter binding of the therapeutic EpCAM-binding antibody, catumaxomab. 26115884 2015
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 Biomarker disease BEFREE TROP-1/Ep-CAM and CD24 are potential candidates for ovarian cancer therapy. 26191160 2015
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 AlteredExpression disease BEFREE The Epithelial Cell Adhesion Molecule (EpCAM) is overexpressed in many cancers including ovarian cancer and EpCAM overexpression correlates with decreased survival of patients. 24489952 2014
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 AlteredExpression disease BEFREE Downregulation of EpCAM expression resulted in growth inhibition in breast cancer, but showed no effect on cell growth in ovarian cancer. 23403823 2013
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 AlteredExpression disease BEFREE Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer. 21694727 2011
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 Biomarker disease CTD_human Incubation with interleukin-2 further increased the cytotoxic activity against EpCAM-positive ovarian cancer cell lines. 20870202 2010
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 AlteredExpression disease BEFREE These results demonstrate high Ep-CAM overexpression in ovarian carcinoma, especially in metastatic and recurrent/chemotherapy-resistant ovarian disease. 19574774 2009
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 Biomarker disease BEFREE While EpCAM-positive exosomes were detectable in both patients with benign ovarian disease and ovarian cancer, exosomal microRNA from ovarian cancer patients exhibited similar profiles, which were significantly distinct from profiles observed in benign disease. 18589210 2008
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.400 AlteredExpression disease BEFREE Furthermore, we provide evidence that the epithelial cell adhesion molecule (EpCAM), known to be overexpressed in ovarian carcinomas, is secreted in exosomes. 17900673 2007