| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.530 | Biomarker | disease | CLINGEN | Exploring 66 cardiac genes using a new custom next-generation sequencing panel, we identified a double heterozygosity for pathogenic mutations in SCN5A and TRPM4 in a Brugada syndrome patient. | 28494446 | 2018 | ||||
|
0.530 | Biomarker | disease | CLINGEN | Mutations in the Trpm4 gene were recently associated with several human conduction disorders such as Brugada syndrome. | 25531103 | 2014 | ||||
|
0.530 | Biomarker | disease | CLINGEN | Dominantly inherited mutations in the TRPM4 gene are associated with the cardiac bundle-branch disorder progressive familial heart block type I (PFHBI) and isolated cardiac conduction disease (ICCD) giving rise to atrio-ventricular conduction block (AVB), right bundle branch block, bradycardia, and the Brugada syndrome. | 24721656 | 2014 | ||||
|
0.530 | Biomarker | disease | CLINGEN | The Trpm4 gene has recently been associated with several disorders, including cardiac conduction diseases and Brugada syndrome. | 24226423 | 2014 | ||||
|
0.530 | GermlineCausalMutation | disease | ORPHANET | TRPM4 mutations account for about 6% of BrS. | 23382873 | 2013 | ||||
|
0.530 | SusceptibilityMutation | disease | ORPHANET | TRPM4 mutations account for about 6% of BrS. | 23382873 | 2013 | ||||
|
0.530 | Biomarker | disease | CLINGEN | TRPM4 mutations account for about 6% of BrS. | 23382873 | 2013 | ||||
|
0.530 | Biomarker | disease | CLINGEN | Mutational spectrum in the Ca(2+)--activated cation channel gene TRPM4 in patients with cardiac conductance disturbances. | 21887725 | 2012 | ||||
|
0.530 | Biomarker | disease | CLINGEN | Among the 45 genotyped patients, only one presented a SCN5A mutation, whereas a TRPM4 mutation was found in another patient.Both belonged to BrS group II. | 23293604 | 2012 |