Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2.1-restricted cytotoxic T lymphocytes. 10897039 2000
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2.1-restricted cytotoxic T lymphocytes. 10897039 2000
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human Increased ErbB-2 tyrosine kinase activity, MAPK phosphorylation, and cell proliferation in the prostate cancer cell line LNCaP following treatment by select pesticides. 11222871 2001
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human Increased ErbB-2 tyrosine kinase activity, MAPK phosphorylation, and cell proliferation in the prostate cancer cell line LNCaP following treatment by select pesticides. 11222871 2001
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. 11248153 2001
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. 11248153 2001
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human HER-2 and topo-isomerase IIalpha as predictive markers in a population of node-positive breast cancer patients randomly treated with adjuvant CMF or epirubicin plus cyclophosphamide. 11583189 2001
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human HER-2 and topo-isomerase IIalpha as predictive markers in a population of node-positive breast cancer patients randomly treated with adjuvant CMF or epirubicin plus cyclophosphamide. 11583189 2001
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human Combining the anti-HER2 antibody trastuzumab with taxanes in breast cancer: results and trial considerations. 11970740 2001
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human Combining the anti-HER2 antibody trastuzumab with taxanes in breast cancer: results and trial considerations. 11970740 2001
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. 12006526 2002
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. 12006526 2002
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human Correlation between HER-2 expression and response to neoadjuvant chemotherapy with 5-fluorouracil, doxorubicin, and cyclophosphamide in patients with breast carcinoma. 12655533 2003
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human Correlation between HER-2 expression and response to neoadjuvant chemotherapy with 5-fluorouracil, doxorubicin, and cyclophosphamide in patients with breast carcinoma. 12655533 2003
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human Epidermal growth factor receptor expression is a candidate target of the synergistic combination of trastuzumab and flavopiridol in breast cancer. 12839951 2003
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human Epidermal growth factor receptor expression is a candidate target of the synergistic combination of trastuzumab and flavopiridol in breast cancer. 12839951 2003
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human Paclitaxel and gemcitabine, as first-line chemotherapy, combined with trastuzumab in patients with advanced breast cancer: a phase II study conducted by the Hellenic Cooperative Oncology Group (HeCOG). 15581045 2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human Paclitaxel and gemcitabine, as first-line chemotherapy, combined with trastuzumab in patients with advanced breast cancer: a phase II study conducted by the Hellenic Cooperative Oncology Group (HeCOG). 15581045 2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human HER2 expression and efficacy of dose-dense anthracycline-containing adjuvant chemotherapy in breast cancer patients. 15970926 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human HER2 expression and efficacy of dose-dense anthracycline-containing adjuvant chemotherapy in breast cancer patients. 15970926 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human Comparison of HER2 status by fluorescence in situ hybridization and immunohistochemistry to predict benefit from dose escalation of adjuvant doxorubicin-based therapy in node-positive breast cancer patients. 15994142 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human Comparison of HER2 status by fluorescence in situ hybridization and immunohistochemistry to predict benefit from dose escalation of adjuvant doxorubicin-based therapy in node-positive breast cancer patients. 15994142 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human Combining lapatinib (GW572016), a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases, with therapeutic anti-ErbB2 antibodies enhances apoptosis of ErbB2-overexpressing breast cancer cells. 16091755 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human Combining lapatinib (GW572016), a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases, with therapeutic anti-ErbB2 antibodies enhances apoptosis of ErbB2-overexpressing breast cancer cells. 16091755 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Therapeutic disease CTD_human HER2 overexpression as a predictive marker in a randomized trial comparing adjuvant cyclophosphamide/methotrexate/5-fluorouracil with epirubicin in patients with stage I/II breast cancer: long-term results. 16137437 2005