Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_human Worse survival for TP53 (p53)-mutated breast cancer patients receiving adjuvant CMF. 15802278 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_human Evaluation of the prognostic and predictive value of p53 and Bcl-2 in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy. 16968874 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_human p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression. 30381462 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_mouse Frequent mutations of the Trp53, Hras1 and beta-catenin (Catnb) genes in 1,3-butadiene-induced mammary adenocarcinomas in B6C3F1 mice. 12165863 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_human The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer. 26229107 2015
Entrez Id: 167465
Gene Symbol: ZNF366
ZNF366 		0.500 Biomarker disease CTD_mouse Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study. 21122099 2010
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		0.500 Biomarker disease CTD_human Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses. 23548910 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_human Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen. 17388661 2007
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		0.500 Biomarker disease CTD_mouse Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K. 25330770 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_human Genomic landscape of cutaneous T cell lymphoma. 26192916 2015
Entrez Id: 167465
Gene Symbol: ZNF366
ZNF366 		0.500 Biomarker disease CTD_human DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer. 20008677 2010
Entrez Id: 1435
Gene Symbol: CSF1
CSF1 		0.310 Biomarker disease BEFREE These results suggest that autocrine and paracrine interactions of the lymphohematopoietic cytokine CSF-1 and its receptor may participate in the biology of human mammary neoplasms. 1829808 1991
Entrez Id: 1435
Gene Symbol: CSF1
CSF1 		0.310 Biomarker disease CTD_human Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts. 16618760 2006
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		0.300 Biomarker disease CTD_human Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer. 28112739 2017
Entrez Id: 9185
Gene Symbol: REPS2
REPS2 		0.300 Biomarker disease CTD_human TMEM25, REPS2 and Meis 1: favourable prognostic and predictive biomarkers for breast cancer. 19776672 2009
Entrez Id: 11118
Gene Symbol: BTN3A2
BTN3A2 		0.300 Biomarker disease CTD_human A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. 29915430 2018
Entrez Id: 60626
Gene Symbol: RIC8A
RIC8A 		0.300 Biomarker disease CTD_human A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. 29915430 2018
Entrez Id: 50618
Gene Symbol: ITSN2
ITSN2 		0.300 Biomarker disease CTD_human Expression profiling identifies genes that predict recurrence of breast cancer after adjuvant CMF-based chemotherapy. 18925433 2009
Entrez Id: 5268
Gene Symbol: SERPINB5
SERPINB5 		0.300 Biomarker disease CTD_human 5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation. 16799634 2007
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		0.300 Biomarker disease CTD_human Associations between aromatase CYP19 rs10046 polymorphism and breast cancer risk: from a case-control to a meta-analysis of 20,098 subjects. 23342035 2013
Entrez Id: 57561
Gene Symbol: ARRDC3
ARRDC3 		0.300 Biomarker disease CTD_human Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1. 25038754 2014
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.300 Biomarker disease CTD_human Nitric oxide produced by inducible nitric oxide synthase is associated with mammary tumorigenesis in irradiated rats. 15631943 2005
Entrez Id: 6160
Gene Symbol: RPL31
RPL31 		0.300 Biomarker disease CTD_human An integrative approach to identify YB-1-interacting proteins required for cisplatin resistance in MCF7 and MDA-MB-231 breast cancer cells. 21466612 2011
Entrez Id: 6423
Gene Symbol: SFRP2
SFRP2 		0.300 Biomarker disease CTD_human Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. 18283316 2008
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		0.300 Biomarker disease CTD_human NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications. 21679465 2011