Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
0.400 GeneticVariation disease BEFREE We investigated the relationship between the brain volume and these two polymorphisms of the SLC6A2 in MDD patients. 26960194 2016
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
0.400 GeneticVariation disease BEFREE 252 unrelated Caucasian patients (f = 142; m = 110) with major depression were genotyped for NET and 5-HTT polymorphisms. 20588071 2010
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
0.400 GeneticVariation disease BEFREE The NET T-182C polymorphism may be in part related to the pathophysiology of major depressive disorder in a Japanese population. 15539861 2004
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
0.400 GeneticVariation disease BEFREE This study suggests that the investigated polymorphisms in the NET gene are not major risk factors in increasing susceptibility to either major depression or its clinical subtypes in a Han Chinese population. 17353941 2007
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
0.400 Biomarker disease BEFREE A total of 26 outpatients with treatment-resistant MDD and 27 matched healthy controls underwent magnetic resonance imaging and genotyping for six SNPs in monoaminergic genes [serotonin transporter (SLC6A4), norepinephrine transporter (SLC6A2), serotonin 1A and 2A receptors (HTR1A and HTR2A), catechol-O-methyltransferase (COMT), and brain-derived neurotrophic factor (BDNF)]. 25990886 2015
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
0.400 GeneticVariation disease BEFREE The sample comprised 426 patients suffering from unipolar MD as well as 643 healthy control subjects for the variants of the 5-HT(1A) receptor and the NET. 19105200 2009
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
0.400 Biomarker disease BEFREE The authors tested norepinephrine transporter availability in patients with major depressive disorder with the aim to identify any associations between test results and clinical symptoms. 27631962 2017
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
0.400 GeneticVariation disease BEFREE Our findings suggest that the NET T-182C and G1287A polymorphisms are not susceptibility factors for MDD. 23648227 2013
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
0.400 GeneticVariation disease BEFREE We conducted an 8-week, open-label, prospective pilot study in 35 patients with major depressive disorder to assess the effects of genetic variations in SLC6A2 and SLC6A4 on both efficacy and side effect profile of desvenlafaxine. 27023264 2016