Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.400 | GeneticVariation | disease | BEFREE | We investigated the relationship between the brain volume and these two polymorphisms of the SLC6A2 in MDD patients. | 26960194 | 2016 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | 252 unrelated Caucasian patients (f = 142; m = 110) with major depression were genotyped for NET and 5-HTT polymorphisms. | 20588071 | 2010 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | The NET T-182C polymorphism may be in part related to the pathophysiology of major depressive disorder in a Japanese population. | 15539861 | 2004 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | This study suggests that the investigated polymorphisms in the NET gene are not major risk factors in increasing susceptibility to either major depression or its clinical subtypes in a Han Chinese population. | 17353941 | 2007 | ||||
|
0.400 | Biomarker | disease | BEFREE | A total of 26 outpatients with treatment-resistant MDD and 27 matched healthy controls underwent magnetic resonance imaging and genotyping for six SNPs in monoaminergic genes [serotonin transporter (SLC6A4), norepinephrine transporter (SLC6A2), serotonin 1A and 2A receptors (HTR1A and HTR2A), catechol-O-methyltransferase (COMT), and brain-derived neurotrophic factor (BDNF)]. | 25990886 | 2015 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | The sample comprised 426 patients suffering from unipolar MD as well as 643 healthy control subjects for the variants of the 5-HT(1A) receptor and the NET. | 19105200 | 2009 | ||||
|
0.400 | Biomarker | disease | BEFREE | The authors tested norepinephrine transporter availability in patients with major depressive disorder with the aim to identify any associations between test results and clinical symptoms. | 27631962 | 2017 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Our findings suggest that the NET T-182C and G1287A polymorphisms are not susceptibility factors for MDD. | 23648227 | 2013 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | We conducted an 8-week, open-label, prospective pilot study in 35 patients with major depressive disorder to assess the effects of genetic variations in SLC6A2 and SLC6A4 on both efficacy and side effect profile of desvenlafaxine. | 27023264 | 2016 |