Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | The present results suggest functionally relevant SLC6A4 promoter hypermethylation as a possibly specific epigenetic marker of MDD, but not of PD itself, and thus might constitute a selective biomarker informing differential diagnosis based on individual epigenetic profiles. | 31353282 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Moreover, we believe this is the first report of a correlation between DNA methylation of the SLC6A4 promoter region and white matter integrity in patients with MDD. | 27505229 | 2016 | ||||
|
0.090 | PosttranslationalModification | disease | BEFREE | Association study of polymorphism in the serotonin transporter gene promoter, methylation profiles, and expression in patients with major depressive disorder. | 27005686 | 2016 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Serotonin transporter gene promoter polymorphisms modify the association between paroxetine serotonin transporter occupancy and clinical response in major depressive disorder. | 18987562 | 2009 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Serotonin transporter gene promoter region polymorphism associated with poststroke major depression. | 16525076 | 2006 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression. | 15520364 | 2004 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Fifty-one patients with major depression were classified for 5-HTT promoter region polymorphism and platelet 5-HTT kinetics before treatment with fluoxetine, and then examined for treatment outcome. | 11983186 | 2002 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide. | 10920459 | 2000 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Children and adolescents with major depression (n = 18) defined by DSM-III-R criteria and normal controls (n = 21) were assessed both for platelet serotonin functionality and for genotypic variants on 5-HTT promoter region. | 10560226 | 1999 |