Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.030 GeneticVariation disease BEFREE The alteration of PI3K can significantly affect the overall patient survival in ESCC but not in esophageal adenocarcinoma (EAC). 28867195 2017
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.030 AlteredExpression disease BEFREE The PI3K/mTOR pathway is upregulated in EAC and may be a target for novel therapies. 27471841 2017
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.030 Biomarker disease BEFREE These results suggest that targeted inhibition of IGFBP2 alone or together with either the MAPK or PI3K/AKT signaling pathway in IGFBP2-overexpressing EAC tumors may be an effective approach for sensitizing resistant EACs to standard neoadjuvant chemotherapy. 26317790 2015