Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
0.030 Biomarker disease BEFREE The present study explores the crosstalk between JAK2 and CXCL12/CXCR4 signaling pathways in MPN. 28903325 2017
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
0.030 Biomarker disease BEFREE In turn, in vivo depletion of nestin(+) cells or their production of CXCL12 expanded mutant HSC number and accelerated MPN progression. 25043017 2014
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
0.030 Biomarker disease BEFREE This study investigated the involvement of chemokines including stromal derived factor 1 (SDF-1), interleukin 8 (IL-8), growth-related oncogene alpha (GRO-alpha) and their receptors, CXCR4, CXCR2 and CXCR1 in essential thrombocythemia (ET), a chronic myeloproliferative disease characterized by megakaryocytic hyperplasia and high platelet count.Fifty-three ET patients were studied. 19006565 2009