Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.100 GeneticVariation disease BEFREE The results of combined analyses indicated that EPHX1 Tyr113His and His139Arg, GSTT1, GSTM1, GSTP1 Ile105Val and Ala114Val were not associated with CRA risk [crude OR (95%CI): 0.98 (0.90-1.07) and P ( z-test) = 0.65 for EPHX1 His carriers vs. Tyr/Tyr; 1.05 (0.97-1.15) and P ( z-test) = 0.21 for EPHX1 Arg carriers vs. His/His; 1.05 (0.92-1.20) and P ( z-test) = 0.47 for GSTT1 Null vs. 22161138 2012
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.100 GeneticVariation disease BEFREE We report the novel associations between P450 genotype and CRA risk, and highlight the risk association with GSTM1 genotype, common to our CRA and cancer case-control series. 20375710 2010
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.100 GeneticVariation disease BEFREE We examined the prevalence of GSTM1 and GSTT1 gene deletions, and two GSTP1 polymorphisms in 772 cases with advanced colorectal adenomas (>1 cm, villous elements or high-grade dysplasia) of the distal colon (descending or sigmoid colon or rectum) and 777 sigmoidoscopy negative controls enrolled in the screening arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. 16030123 2005
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.100 GeneticVariation disease BEFREE The GSTM1 and GSTT1 genotypes did not seem to modify the association between cruciferous vegetable intake and colorectal adenomas. 16365014 2005
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.100 GeneticVariation disease BEFREE Neither age at diagnosis of colorectal adenomas nor occurrence of extra-intestinal tumors differed significantly between genotypes at the NAT2 and GSTM1 loci, whereas GSTT1 polymorphism showed an uncertain association with extra-intestinal manifestations. 11773864 2002
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.100 GeneticVariation disease BEFREE The present findings do not support the role for GSTM1 and GSTT1 genotypes in the development of colorectal adenomas. 11165755 2001
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.100 GeneticVariation disease BEFREE The positive association between smoking and colorectal adenomas did not vary much with GSTM1 genotypes. 10919645 2000
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.100 Biomarker disease BEFREE One study suggests a strong inverse relation between colorectal adenomas and broccoli consumption, particularly in subjects who are GSTM1 null.These finding require confirmation. 10625170 2000
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.100 GeneticVariation disease BEFREE We hypothesized that broccoli consumption in combination with the glutathione transferase M1 (GSTM1) null genotype would be associated with a lower prevalence of colorectal adenomas because of higher isothiocyanate levels. 9718215 1998
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
0.100 GeneticVariation disease BEFREE We observed no overall effect of the GSTM1 null genotype on the risk for colorectal adenomas (odds ratio, 0.85; 95% confidence interval = 0.65-1.10). 7882312 1995