Gene: GABPA ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker disease BEFREE Nestin regulates cellular redox homeostasis in lung cancer through the Keap1-Nrf2 feedback loop. 31695040 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker disease BEFREE miR‑144‑3p regulates the resistance of lung cancer to cisplatin by targeting Nrf2. 30542710 2018
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker disease BEFREE Here we summarize the recent advances in NRF2-addicted lung cancer. 31574294 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker disease BEFREE A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. 28504720 2017
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker disease BEFREE The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer. 28976703 2018
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker disease BEFREE These findings suggest that HO-1 may modulate the chemosensitivity of lung cancer A549 cells to cisplatin through the MAPK-Nrf2 pathway. 18006113 2008
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker disease BEFREE Finally, Nrf2 seems to be essential for the hyper proliferation of lung cancer cells in the absence of EZH2. 24928441 2014
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 AlteredExpression disease BEFREE Human lung cancer biopsies expressed higher levels of Nrf2 and HO-1 compared with normal tissues. 31227482 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 AlteredExpression disease BEFREE Mechanically, we identify Nrf2, which is a core transcription factor for lung cancer growth and drug resistance, as a target of SIRT5. 25070488 2014
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 AlteredExpression disease BEFREE Nrf2 expression levels may be associated with prognosis of lung cancer, but previous results have been inconsistent. 31298052 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 AlteredExpression disease BEFREE This study investigated the expression of Nrf2 and of Nrf2-targeted genes (NQO1 and GCLC) and the genes for the metallothionein (MT) isoforms (MT-1A and MT-2A) in human lung cancer and cancer-surrounding tissues. 23947958 2013