This was a retrospective study of 238 patients, including 92 with type-2 DM (DM2) and 11 with type-1 DM (DM1), having routine whole body FDG PET/CT.Patients with lymphoma were excluded.
Comparisons of CT features and <sup>18</sup>F-FDG metabolic indices between benign and malignant entities, as well as among primary and secondary malignancies and lymphoma, were performed.
Burkitt's lymphoma is a lymphoma with unclear metabolic behavior at 18F-FDG-PET/CT and no validated criteria in treatment evaluation and prediction of outcome exist.
Although <sup>18</sup>F-FDG has proved useful in the management of patients with lymphoma, the specificity of <sup>18</sup>F-FDG uptake has been critically questioned, and is not without flaws.
18-Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG PET/CT) is currently the criterion standard of lymphoma imaging and recommended through all stages of Hodgkin lymphoma management.
FDG uptake in the lymph nodes was observed in 53.3% of the patients with lymphoma and 43.3% of the patients without lymphoma, with no difference in the number of sites, uptake pattern, or mean SUVmax.
Interim and posttreatment sequential FDG PET/CT scans revealed a residual splenic mass showing markedly intense FDG uptake suspected of a residual viable lymphoma.
[<sup>18</sup>F]FB-GAcDb immunoPET was further evaluated in a disseminated lymphoma (A20-hCD20) syngeneic for hCD20TM and compared to [<sup>18</sup>F]FDG PET.
In this case, we aim to highlight this interesting FDG PET/CT imaging finding, which can serve as a clue allowing one to strongly suggest lymphoma as the leading diagnosis.
Except for SUVmin (<i>p</i>=0.971), the averages of FDG uptake metrics of lymphoma were significantly higher than those of carcinoma (<i>p</i> ≤ 0.001), with the following median values: SUV<sub>mean</sub>, 4.75 versus 2.38 g/ml (<i>P</i> < 0.001); SUV<sub>std</sub>, 2.04 versus 0.88 g/ml (<i>P</i>=0.001); SUV<sub>max</sub>, 10.69 versus 4.76 g/ml (<i>P</i>=0.001); SUV<sub>peak</sub>, 9.15 versus 2.78 g/ml (<i>P</i> < 0.001); TLG, 42.24 versus 9.90 (<i>P</i> < 0.001).
Predictions of outcome after first-line treatment for DLBCL were surprisingly good when left to the unsupervised, subjective judgment of experienced readers of lymphoma 18F-FDG-PET/CT.
The impact of early fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET-CT) status on survival after allogeneic transplantation for lymphoma is poorly reported.
Since the introduction of FDG-PET for the staging and restaging of patients with lymphoma, a high predictive value of F-18-FDG-PET in response assessment has been observed.
Two types of metabolic behavior were therefore identified using F-choline and F-FDG which corresponded to 2 different uptake patterns, that is, those of the prostate and lymphoma tumoral cell contingents.
The 18F-FDG positron-emission tomography (PET) and contrast-enhanced computerised tomography (CECT) data of all relapsed or refractory HL treated at Gustave Roussy, Villejuif, France, from 2013 to 2015 were retrospectively reviewed according to the International Harmonisation Project Cheson 2014 criteria and the LYmphoma Response to Immunomodulatory therapy Criteria (LYRIC).