Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 56287
Gene Symbol: GKN1
GKN1
0.010 Biomarker disease BEFREE <b>Conclusion:</b> The identification of additional lesions outside the R-FOV (eyes to thighs) using <sup>18</sup>F-FDG PET/CT has no impact in the definition of the clinical stage of disease and minimal impact in the treatment definition of patients with pediatric lymphoma. 30683766 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.100 Biomarker disease BEFREE <b>Conclusion:</b> The identification of additional lesions outside the R-FOV (eyes to thighs) using <sup>18</sup>F-FDG PET/CT has no impact in the definition of the clinical stage of disease and minimal impact in the treatment definition of patients with pediatric lymphoma. 30683766 2019
Entrez Id: 4233
Gene Symbol: MET
MET
0.040 Biomarker disease BEFREE <b>Conclusion:</b><sup>11</sup>C-MET uptake is elevated in most regions involved with lymphoma at diagnosis and follow-up. 27609791 2017
Entrez Id: 2026
Gene Symbol: ENO2
ENO2
0.020 Biomarker disease BEFREE <b>Conclusions:</b> These results indicate that NSE may be a potential target for lymphoma therapy and a prognosis marker for lymphoma. 31191019 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
0.100 AlteredExpression disease BEFREE <b>Purpose:</b> Activation of the PI3K/mTOR signaling pathway is recurrent in different lymphoma types, and pharmacologic inhibition of the PI3K/mTOR pathway has shown activity in lymphoma patients. 29066507 2018
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.100 AlteredExpression disease BEFREE <b>Purpose:</b> Activation of the PI3K/mTOR signaling pathway is recurrent in different lymphoma types, and pharmacologic inhibition of the PI3K/mTOR pathway has shown activity in lymphoma patients. 29066507 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.100 AlteredExpression disease BEFREE <b>Purpose:</b> Activation of the PI3K/mTOR signaling pathway is recurrent in different lymphoma types, and pharmacologic inhibition of the PI3K/mTOR pathway has shown activity in lymphoma patients. 29066507 2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
0.100 AlteredExpression disease BEFREE <b>Purpose:</b> Activation of the PI3K/mTOR signaling pathway is recurrent in different lymphoma types, and pharmacologic inhibition of the PI3K/mTOR pathway has shown activity in lymphoma patients. 29066507 2018
Entrez Id: 6737
Gene Symbol: TRIM21
TRIM21
0.010 GeneticVariation disease BEFREE <i>HCP5</i> rs3099844 was associated with anti-SSA (<i>P</i> = 0.006, OR = 3.07) and anti-SSB (<i>P</i> = 0.005, OR = 2.66) antibodies, severity of focus score (<i>P</i> = 0.03, OR = 12), and lymphoma development (<i>P</i> = 0.002, OR = 7.23). 30882006 2019
Entrez Id: 811
Gene Symbol: CALR
CALR
0.010 GeneticVariation disease BEFREE <i>HCP5</i> rs3099844 was associated with anti-SSA (<i>P</i> = 0.006, OR = 3.07) and anti-SSB (<i>P</i> = 0.005, OR = 2.66) antibodies, severity of focus score (<i>P</i> = 0.03, OR = 12), and lymphoma development (<i>P</i> = 0.002, OR = 7.23). 30882006 2019
Entrez Id: 6741
Gene Symbol: SSB
SSB
0.010 GeneticVariation disease BEFREE <i>HCP5</i> rs3099844 was associated with anti-SSA (<i>P</i> = 0.006, OR = 3.07) and anti-SSB (<i>P</i> = 0.005, OR = 2.66) antibodies, severity of focus score (<i>P</i> = 0.03, OR = 12), and lymphoma development (<i>P</i> = 0.002, OR = 7.23). 30882006 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.100 Biomarker disease BEFREE <sup>18</sup>F-FDG PET/CT in Lymphoma: Has Imaging-Directed Personalized Medicine Become a Reality? 28798034 2017
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.100 Biomarker disease BEFREE <sup>18</sup>F-FDG PET/CT also detected an unsuspected synchronous lymphoma in 1 patient. 30237211 2019
Entrez Id: 695
Gene Symbol: BTK
BTK
0.100 Biomarker disease BEFREE (S)-N-Boc-3-hydroxypiperidine ((S)-NBHP) is a key pharmaceutical intermediate and the chiral source in synthesizing Imbruvica, which is a newly approved drug in lymphoma therapy by targeting Bruton's tyrosine kinase (BTK). 27854034 2017
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.100 Biomarker disease BEFREE 18-Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG PET/CT) is currently the criterion standard of lymphoma imaging and recommended through all stages of Hodgkin lymphoma management. 30247256 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.100 Biomarker disease BEFREE 18F-FDG-PET/CT has become a standard for assessing treatment response in patients with lymphoma. 30284376 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
0.100 GeneticVariation disease BEFREE 2019; published online January 28, https://doi.org/10.1038/s41588-018-0338-y) examined the effects of mutant EZH2 on the 3D architecture of the lymphoma genome, highlighting the potential relevance of chromatin folding dynamics. 30885427 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.100 Biomarker disease BEFREE 4E-BP1 expression was also demonstrable in all 4 lymph nodes with in situ or partial involvement by follicular lymphoma and in all 12 cases of BCL2-negative lymphoma. 21366462 2011
Entrez Id: 1822
Gene Symbol: ATN1
ATN1
0.030 Biomarker disease BEFREE Lymphoma growth was also inhibited in SB203580-treated NOD-SCID mice. 12756297 2003
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
0.020 Biomarker disease BEFREE Lymphoma immunotherapy with CpG oligodeoxynucleotides requires TLR9 either in the host or in the tumor itself. 17675511 2007
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.100 GeneticVariation disease BEFREE Lymphoma viability remained unaffected by the genetic deletion or pharmacological inhibition of all alternative BCL-2 family members. 27055871 2016
Entrez Id: 1235
Gene Symbol: CCR6
CCR6
0.010 AlteredExpression disease BEFREE Lymphoma patients showed increased numbers of cTfh1 and reduced cTfh17 cells due to decreased expression of the subset-defining marker CCR6 in patients. 29293620 2018
Entrez Id: 100313843
Gene Symbol: MIR711
MIR711
0.010 Biomarker disease BEFREE Lymphoma-induced chronic itch is suppressed by miR-711 inhibitor and a blocking peptide that disrupts the miR-711/TRPA1 interaction. 30033153 2018
Entrez Id: 100
Gene Symbol: ADA
ADA
0.030 AlteredExpression disease BEFREE Lymphoma should be kept in mind in the differential diagnosis in patients with lymphocytic pleural effusion and high ADA levels. 31555687 2019
Entrez Id: 200081
Gene Symbol: TXLNA
TXLNA
0.020 AlteredExpression disease BEFREE Lymphoma B cells placed at low serum and cell density proliferated in vitro to either purified IL-14 or IL-14 derived from effusion fluids. 7795235 1995