Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE The clinicopathologic characteristics, immunophenotype, EBV in situ hybridization, and T cell receptor (TCR) gene rearrangement of primary pulmonary NK cell lymphoma from a 73-year-old Chinese woman were investigated and the clonal status was determined using female X-chromosomal inactivation mosaicism and polymorphisms at the phosphoglycerate kinase (PGK) gene. 23958352 2013
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE The aim of this study was to investigate the clinicopathologic features, immunophenotype, T cell receptor (TCR) gene rearrangement, the association with Epstein-Barr virus (EBV) infection and p53 gene mutations of the lymphoma. 23557559 2013
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE Immunoglobulin heavy chain (IgH) or T-cell receptor (TCR) gene rearrangement is observed in B-cell or T-cell primary vitreoretinal lymphoma, respectively. 22834783 2012
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE Strikingly, this unique TCR-independent killing is induced through lymphoma MHC-I engagement. 21753148 2011
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 AlteredExpression disease BEFREE Ig/TCR VDJ errors are also at the origin of recombinase mediated deregulated expression of a variety of proto-oncogenes in ALL, whereas in lymphoma it is increasingly clear that IgH containing translocations result from abnormalities other than VDJ errors (somatic hypermutation and/or isotype switching). 19731811 2009
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE The predominant lymphoma types found in these 14 NBS children were diffuse large B cell lymphoma (DLBCL) and T cell lymphoblastic lymphoma (T-LBL/ALL), all showing monoclonal Ig/TCR rearrangements. 18788073 2008
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE We show that, in a line of TCR transgenic TG-B mice, an insertional mutation in one allele of the Epm2a locus and epigenetic silencing of another led to a high rate of lymphoma with early onset. 16959610 2006
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE Incorporating the results of immunoglobulin heavy chain (IgH) and T-cell receptor (TCR) gene rearrangements enabled diagnosis of lymphoma in 17 patients, including 5 of the 6 patients suspected to have NHL or an atypical lymphoid proliferation. 16533955 2006
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE EBV- TCR- lymphoma showed less necrosis (P = 0.0133) and a better 2-year survival rate (P = 0.0066) than EBV+ TCR- lymphoma. 15139996 2004
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE However, the lineage assignment of sinonasal lymphoma with a monoclonal TCR-gamma rearrangement is unclear because of its mixed NK/T phenotype. 12533686 2003
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE Sixty cases with a confirmed histological diagnosis of a T-cell lymphoproliferative disorder and TCR gamma GR were identified in our lymphoma registry from 1995 to 2001. 12707372 2003
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE To determine whether CD8 independent tumor cell recognition is a property of the TCR, we used retroviral transduction to express the TIL 1383I TCR in the CD8(-) murine lymphoma, 58 alpha(-)/beta(-). 12594285 2003
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE Angioimmunoblastic T cell lymphoma (AILT) is a rare lymphoma that is regarded as a clinicopathologic entity but shows considerable histomorphologic diversity, variable immunophenotypes and inconsistent T cell receptor (TCR) gene rearrangement. 12455048 2003
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE Characterization of lymphoma and gastritis areas of seven gastrectomy specimens using a T-cell receptor beta variable chain (TCR betaV) family-specific reverse transcriptase (RT)-polymerase chain reaction (PCR) assay and fluorescence-activated cell sorter (FACS) analysis revealed a local chronic and acute activation of T cells in lymphoma and an oligoclonal T-cell repertoire in gastritis and in lymphoma, partially sharing the same clones. 10565685 1999
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE Characterization of the clonality of non-Hodgkin's lymphoma (NHL) by the rearranged segments of immunoglobulin heavy chain (Ig(H)) or T cell receptor (TCR) genes is not only useful in the confirmation of the diagnosis but also for the future assessment of how a secondary lymphoma, such as a recurrence or another primary lymphoma, occurs. 10355963 1999
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE Southern analysis and polymerase chain reaction (PCR) were used to detect the rearranged V-D-J segment of T-cell receptor delta (TCR delta) gene from malignant cell specimens of patients with leukemia and lymphoma of T-cell lineage. 9209365 1997
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE T-cell receptor delta (TCR-delta) gene rearrangement was studied in 40 cases of acute leukaemia and lymphoma of T-cell lineage at diagnosis. 8756082 1996
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE DNA studies of the lymphoma at the first presentation demonstrated dual rearrangement in the T-cell receptor beta (TCR beta) and immunoglobulin heavy chain J region (IgJH) genes. 8299098 1994
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE Neither DNA flow cytometry nor TCR gene rearrangement can predict the 15% to 19% of patients in whom a lymphoma will develop. 8288780 1994
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE CD43 antigen was positive, and rearrangement of TCR-beta gene was observed.The lymphoma was the T-cell type. 8127156 1994
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 AlteredExpression disease BEFREE This prompted us to investigate lymphoma biopsies from 7 non-Oriental patients with NTCL for the expression of natural killer (NK) and T-cell antigens, including TCR proteins, for the presence of EBV-encoded latent membrane protein (LMP) using immunohistochemistry and for the presence of EBV DNA and Epstein-Barr early region (EBER) RNA using in situ hybridization (ISH). 8387835 1993
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE Nine patients had acute lymphoblastic leukaemia (T-ALL), nine patients had prolymphocytic leukaemia (PLL), six patients presented with a T-CLL/T-lymphocytosis syndrome, two patients had Sezary syndrome (SS) and one patient had HTLV-I positive T-cell leukaemia/lymphoma (ATLL). alpha TCR gene rearrangement could be demonstrated by the use of three available probes in only one case. 2961364 1987