Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
0.050 Biomarker disease BEFREE We recently identified the oncogenes/tumor suppressors Wilms Tumor Suppressor 1 (WT1) and Early Growth Response 1 (EGR1) as regulators of the expression of STIM1, an essential regulator of Ca(2+) entry in non-excitable cells. 21622185 2011
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
0.050 Biomarker disease BEFREE Analysis of the STIM1 promoter using the TESS search system (University of Pennsylvania) revealed four putative response elements to the zinc-finger proteins WT1 (Wilms tumor suppressor 1) and EGR1 (early growth response 1). 20123987 2010
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
0.050 AlteredExpression disease BEFREE However, recent reports have clarified that early growth response 1 gene (Egr1) positively regulates MDR1 transcription, while Wilms' tumor suppressor gene (WT1) does negative regulation of MDR1 gene expression in 12-O-tetradecanoylphorbol-13-acetate treated K562 cells. 11734301 2002
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
0.050 AlteredExpression disease BEFREE EGR-1 was expressed in normal kidney tissues and in the three main cell types of Wilms' tumor. 11106242 2000
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
0.050 GeneticVariation disease BEFREE The wt1 gene, a putative tumor suppressor gene located at the Wilms tumor (WT) locus on chromosome 11p13, encodes a zinc finger-containing protein that binds to the same DNA sequence as EGR-1, a mitogen-inducible immediate-early gene product that activates transcription. 1654597 1991