Gene: MLH1 ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 GeneticVariation disease CLINVAR Inhibition of aldehyde reductase by acidic metabolites of the biogenic amines. 16 1975
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Secretion of alpha-immunoreactive inhibin by human pre-embryos cultured in vitro. 1522200 1992
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. 7704024 1995
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Mutation screening in the hMLH1 gene in Swedish hereditary nonpolyposis colon cancer families. 8521398 1995
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR CpG dinucleotides in the hMSH2 and hMLH1 genes are hotspots for HNPCC mutations. 8566964 1996
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16. 8571956 1996
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 GeneticVariation disease CLINVAR Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. 8574961 1996
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. 8574961 1996
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR DNA mismatch repair gene mutations in 55 kindreds with verified or putative hereditary non-polyposis colorectal cancer. 8776590 1996
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Germline mutations of hMLH1 and hMSH2 genes in Korean hereditary nonpolyposis colorectal cancer. 8797773 1996
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer. 8872463 1996
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Mutation screening of MSH2 and MLH1 mRNA in hereditary non-polyposis colon cancer syndrome. 8880570 1996
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Characterization of MSH2 and MLH1 mutations in Italian families with hereditary nonpolyposis colorectal cancer. 8993976 1997
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Germline HNPCC gene variants have little influence on the risk for sporadic colorectal cancer. 9032648 1997
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Mean age of tumor onset in hereditary nonpolyposis colorectal cancer (HNPCC) families correlates with the presence of mutations in DNA mismatch repair genes. 9218993 1997
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Hereditary nonpolyposis colorectal cancer (HNPCC): eight novel germline mutations in hMSH2 or hMLH1 genes. 9298827 1997
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations. 9311737 1997
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Mutations in beta-catenin are uncommon in colorectal cancer occurring in occasional replication error-positive tumors. 9377556 1997
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae. 9697702 1998
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 GeneticVariation disease CLINVAR Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae. 9697702 1998
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls. 9718327 1998
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR Microsatellite instability and mutation of DNA mismatch repair genes in gliomas. 9777949 1998
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 GeneticVariation disease CLINVAR Excess of hMLH1 germline mutations in Swiss families with hereditary non-polyposis colorectal cancer. 9833759 1998
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 GeneticVariation disease CLINVAR The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer. 10037723 1999
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.900 CausalMutation disease CLINVAR The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer. 10037723 1999