×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.
28135145
2017
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
Homozygous inactivation of CHEK2 is linked to a familial case of multiple primary lung cancer with accompanying cancers in other organs.
27900359
2016
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells.
24976383
2014
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
Meta-analysis of CHEK2 1100delC variant and colorectal cancer susceptibility.
21807500
2011
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
CHEK2 mutations and HNPCC-related colorectal cancer.
19876921
2010
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
The CHEK2 gene I157T mutation and other alterations in its proximity increase the risk of sporadic colorectal cancer in the Czech population.
18996005
2009
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
In contrast, CHEK2 1100delC was present in 10 of 237 (4.2%) HNPCC /HNPCC -related cases that was significantly more prevalent than the 1.0% Dutch population frequency (odds ratio, 4.3; 95% confidence interval, 1.7-10.7; P = 0.002).
18676774
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
Alterations of Chk1 and Chk2 expression in colon cancer.
18679694
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
DNA damage during reoxygenation elicits a Chk2-dependent checkpoint response.
16478982
2006
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
15829956
2005
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
Homozygosity for a CHEK2*1100delC mutation identified in familial colorectal cancer does not lead to a severe clinical phenotype.
15818573
2005
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
0.330
Biomarker
disease
CLINGEN
The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype.
12690581
2003