Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
0.350 Biomarker disease CLINGEN Molecular characteristics of mismatch repair genes in sporadic colorectal tumors in Czech patients. 24484585 2014
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
0.350 Biomarker disease CLINGEN Because of functional similarity to Fen1, and because Exo1 is involved in DNA mismatch repair (MMR) by interaction with Msh2 and Mlh1, genes that cause hereditary nonpolyposis colorectal cancer (HNPCC), we investigated the possibility that Exo1 might also act as a modifier to Apc(1638N). 17452984 2007
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
0.350 Biomarker disease CLINGEN Thus, little evidence was obtained to support a major causative role of EXO1 in HNPCC, although we cannot exclude a role for EXO1 as a low penetrance cancer susceptibility or modifying gene. 12517792 2003
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
0.350 Biomarker disease CLINGEN Evidence made available in this study sheds light on the pathogenesis of HNPCC, perhaps initiated by an additional MMR gene, hEXO1. 12414623 2002
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
0.350 Biomarker disease CLINGEN HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes. 11429708 2001
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
0.350 Biomarker disease CLINGEN Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis. 10856833 2000