Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.300 | Biomarker | disease | CLINGEN | Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer. | 28135145 | 2017 | ||||
|
0.300 | Biomarker | disease | CLINGEN | Homozygous inactivation of CHEK2 is linked to a familial case of multiple primary lung cancer with accompanying cancers in other organs. | 27900359 | 2016 | ||||
|
0.300 | Biomarker | disease | CLINGEN | Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells. | 24976383 | 2014 | ||||
|
0.300 | Biomarker | disease | CLINGEN | Meta-analysis of CHEK2 1100delC variant and colorectal cancer susceptibility. | 21807500 | 2011 | ||||
|
0.300 | Biomarker | disease | CLINGEN | CHEK2 mutations and HNPCC-related colorectal cancer. | 19876921 | 2010 | ||||
|
0.300 | Biomarker | disease | CLINGEN | The CHEK2 gene I157T mutation and other alterations in its proximity increase the risk of sporadic colorectal cancer in the Czech population. | 18996005 | 2009 | ||||
|
0.300 | Biomarker | disease | CLINGEN | CHEK2 1100delC is a susceptibility allele for HNPCC-related colorectal cancer. | 18676774 | 2008 | ||||
|
0.300 | Biomarker | disease | CLINGEN | Alterations of Chk1 and Chk2 expression in colon cancer. | 18679694 | 2008 | ||||
|
0.300 | Biomarker | disease | CLINGEN | DNA damage during reoxygenation elicits a Chk2-dependent checkpoint response. | 16478982 | 2006 | ||||
|
0.300 | Biomarker | disease | CLINGEN | DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. | 15829956 | 2005 | ||||
|
0.300 | Biomarker | disease | CLINGEN | Homozygosity for a CHEK2*1100delC mutation identified in familial colorectal cancer does not lead to a severe clinical phenotype. | 15818573 | 2005 | ||||
|
0.300 | Biomarker | disease | CLINGEN | The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype. | 12690581 | 2003 |