Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 84432
Gene Symbol: PROK1
PROK1 		0.010 AlteredExpression disease BEFREE PRK1 distribution in normal tissues and carcinomas: overexpression and activation in ovarian serous carcinoma. 19427017 2009
Entrez Id: 5076
Gene Symbol: PAX2
PAX2 		0.010 AlteredExpression disease BEFREE PAX2 was found to be one of the most upregulated genes in low-grade ovarian serous carcinoma. 19525924 2009
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2 		0.010 Biomarker disease BEFREE HMGA2: a biomarker significantly overexpressed in high-grade ovarian serous carcinoma. 20228781 2010
Entrez Id: 51773
Gene Symbol: RSF1
RSF1 		0.020 Biomarker disease BEFREE Rsf-1 (HBXAP) has been reported as an amplified gene in human cancer, including the highly aggressive ovarian serous carcinoma. 20923775 2010
Entrez Id: 79923
Gene Symbol: NANOG
NANOG 		0.020 AlteredExpression disease BEFREE NANOG expression was also measured immunohistochemically in a tissue microarray containing ovarian tissues from 74 patients with ovarian serous carcinoma and 24 with ovarian serous cystadenoma. 23095773 2012
Entrez Id: 9212
Gene Symbol: AURKB
AURKB 		0.020 AlteredExpression disease BEFREE Aurora B expression in metastatic effusions from advanced-stage ovarian serous carcinoma is predictive of intrinsic chemotherapy resistance. 23114921 2013
Entrez Id: 811
Gene Symbol: CALR
CALR 		0.010 AlteredExpression disease BEFREE Calreticulin expression is reduced in high-grade ovarian serous carcinoma effusions compared with primary tumors and solid metastases. 24060004 2013
Entrez Id: 6323
Gene Symbol: SCN1A
SCN1A 		0.020 AlteredExpression disease BEFREE Nac1 (nucleus accumbens 1) is a POZ (poxvirus and zinc finger)-domain transcriptional repressor that is expressed at high levels in ovarian serous carcinoma. 24702277 2014
Entrez Id: 112939
Gene Symbol: NACC1
NACC1 		0.020 AlteredExpression disease BEFREE Nac1 (nucleus accumbens 1) is a POZ (poxvirus and zinc finger)-domain transcriptional repressor that is expressed at high levels in ovarian serous carcinoma. 24702277 2014
Entrez Id: 699
Gene Symbol: BUB1
BUB1 		0.010 AlteredExpression disease BEFREE BUB1 mRNA is significantly co-expressed with AURKA and AURKB mRNA in advanced-stage ovarian serous carcinoma. 24756216 2014
Entrez Id: 335
Gene Symbol: APOA1
APOA1 		0.010 AlteredExpression disease BEFREE APOA1 mRNA expression in ovarian serous carcinoma effusions is a marker of longer survival. 24926085 2014
Entrez Id: 57019
Gene Symbol: CIAPIN1
CIAPIN1 		0.010 Biomarker disease BEFREE CIAPIN1 and ABCA13 are markers of poor survival in metastatic ovarian serous carcinoma. 25889687 2015
Entrez Id: 238
Gene Symbol: ALK
ALK 		0.310 AlteredExpression disease BEFREE ALK expression was detected in 23/85 (27.1%) ovarian serous carcinoma and 0/25 (0%) in ovarian mucinous carcinoma. 27271776 2016
Entrez Id: 8764
Gene Symbol: TNFRSF14
TNFRSF14 		0.010 Biomarker disease BEFREE HVEM can provide a basis in the search for a new targeting treatment for ovarian serous adenocarcinoma. 28365939 2017
Entrez Id: 6768
Gene Symbol: ST14
ST14 		0.010 AlteredExpression disease BEFREE Matriptase expression was analyzed in 80 ovarian serous adenocarcinoma and 12 normal ovarian tissue samples by immunohistochemistry. 28454318 2017
Entrez Id: 7849
Gene Symbol: PAX8
PAX8 		0.020 Biomarker disease BEFREE PAX8 Expression in a Subset of Malignant Peritoneal Mesotheliomas and Benign Mesothelium has Diagnostic Implications in the Differential Diagnosis of Ovarian Serous Carcinoma. 28877056 2017
Entrez Id: 407008
Gene Symbol: MIR223
MIR223 		0.010 Biomarker disease BEFREE miR-223 potentially targets SWI/SNF complex protein SMARCD1 in atypical proliferative serous tumor and high-grade ovarian serous carcinoma. 29079174 2017
Entrez Id: 6909
Gene Symbol: TBX2
TBX2 		0.010 AlteredExpression disease BEFREE TBX2 expression may serve as a predictive marker of the efficacy of platinum-based chemotherapy for patients with ovarian serous carcinoma. 29435041 2018
Entrez Id: 7351
Gene Symbol: UCP2
UCP2 		0.010 AlteredExpression disease BEFREE UCP2 expression may be a predictive marker of the efficacy of platinum-based chemotherapy for patients with ovarian serous carcinoma. 29928365 2018
Entrez Id: 94025
Gene Symbol: MUC16
MUC16 		0.020 Biomarker disease BEFREE CA125 and p53 are reliable markers that are useful for differentiating both uterine serous and ovarian serous carcinoma from their most common subtypes (endometrioid type carcinoma of ovary and uterus) but so far there is no histopathologic marker that differentiates USC from OSC. 31165997 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.020 GeneticVariation disease BEFREE Activation of MAPK is regulated by upstream kinases including KRAS and BRAF, which are frequently mutated in low-grade ovarian serous carcinoma. 15475429 2004
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.020 GeneticVariation disease BEFREE Activation of MAPK is regulated by upstream kinases including KRAS and BRAF, which are frequently mutated in low-grade ovarian serous carcinoma. 15475429 2004
Entrez Id: 4047
Gene Symbol: LSS
LSS 		0.010 GeneticVariation disease BEFREE Advanced-stage ovarian serous carcinoma (OSC) generally have poor prognosis. 23836287 2013
Entrez Id: 3778
Gene Symbol: KCNMA1
KCNMA1 		0.010 Biomarker disease BEFREE Amplification of KCNMA1 was restricted to a small but distinct fraction of breast, ovarian and endometrial cancer with the highest prevalence in invasive ductal breast cancers and serous carcinoma of ovary and endometrium (3-7%). 22899999 2012
Entrez Id: 6482
Gene Symbol: ST3GAL1
ST3GAL1 		0.010 AlteredExpression disease BEFREE An increased expression of ST3Gal I may contribute directly to increased alpha2,3-linked sialylation in ovarian serous carcinoma. 16112178 2005