Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55055
Gene Symbol: ZWILCH
ZWILCH 		0.100 GeneticVariation disease GWASCAT Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. 28604728 2017
Entrez Id: 27332
Gene Symbol: ZNF638
ZNF638 		0.100 GeneticVariation disease GWASCAT Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. 28604728 2017
Entrez Id: 113835
Gene Symbol: ZNF257
ZNF257 		0.100 GeneticVariation disease GWASCAT Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor. 28604732 2017
Entrez Id: 161882
Gene Symbol: ZFPM1
ZFPM1 		0.110 GeneticVariation disease GWASCAT Identification of four new susceptibility loci for testicular germ cell tumour. 26503584 2015
Entrez Id: 161882
Gene Symbol: ZFPM1
ZFPM1 		0.110 GeneticVariation disease BEFREE We identified new risk loci for TGCT at 3q23 (rs11705932, TFDP2, P=1.5 × 10(-9)), 11q14.1 (rs7107174, GAB2, P=9.7 × 10(-11)), 16p13.13 (rs4561483, GSPT1, P=1.6 × 10(-8)) and 16q24.2 (rs55637647, ZFPM1, P=3.4 × 10(-9)). 26503584 2015
Entrez Id: 161882
Gene Symbol: ZFPM1
ZFPM1 		0.110 GeneticVariation disease GWASCAT Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. 28604728 2017
Entrez Id: 161882
Gene Symbol: ZFPM1
ZFPM1 		0.110 GeneticVariation disease GWASCAT Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor. 28604732 2017
Entrez Id: 55734
Gene Symbol: ZFP64
ZFP64 		0.100 GeneticVariation disease GWASCAT Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. 28604728 2017
Entrez Id: 132625
Gene Symbol: ZFP42
ZFP42 		0.100 GeneticVariation disease GWASCAT Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. 28604728 2017
Entrez Id: 132625
Gene Symbol: ZFP42
ZFP42 		0.100 GeneticVariation disease GWASCAT Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor. 28604732 2017
Entrez Id: 7503
Gene Symbol: XIST
XIST 		0.020 AlteredExpression disease BEFREE The current study was designed to shed light on the question whether the multiple X chromosomes in testicular germ cell tumor are active or inactive through a complex mechanism of X chromosomal gain and XIST expression. 12629412 2003
Entrez Id: 7503
Gene Symbol: XIST
XIST 		0.020 AlteredExpression disease BEFREE In addition, imprinting defects, DNA hypomethylation of testis/cancer associated genes, and the presence of unmethylated XIST are frequent in TGCTs. 18042148 2007
Entrez Id: 7490
Gene Symbol: WT1
WT1 		0.010 Biomarker disease BEFREE Intriguingly, RoH200 at 11p13-11p14.3 encompasses Wilms tumour 1 (WT1), a recognized cancer susceptibility gene with roles in sex determination and developmental transcriptional regulation, processes repeatedly implicated in TGCT aetiology. 31310061 2019
Entrez Id: 7405
Gene Symbol: UVRAG
UVRAG 		0.010 Biomarker disease BEFREE Cytokeratin 7, inhibin, and p63 in testicular germ cell tumor: superior markers of choriocarcinoma compared to β-human chorionic gonadotropin. 30359635 2019
Entrez Id: 7371
Gene Symbol: UCK2
UCK2 		0.110 GeneticVariation disease GWASDB Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14. 23666240 2013
Entrez Id: 7371
Gene Symbol: UCK2
UCK2 		0.110 GeneticVariation disease GWASCAT Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. 28604728 2017
Entrez Id: 7371
Gene Symbol: UCK2
UCK2 		0.110 GeneticVariation disease GWASCAT Two new loci and gene sets related to sex determination and cancer progression are associated with susceptibility to testicular germ cell tumor. 25877299 2015
Entrez Id: 7371
Gene Symbol: UCK2
UCK2 		0.110 GeneticVariation disease BEFREE Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23. 23462292 2013
Entrez Id: 7371
Gene Symbol: UCK2
UCK2 		0.110 GeneticVariation disease GWASCAT Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor. 28604732 2017
Entrez Id: 494514
Gene Symbol: TYMSOS
TYMSOS 		0.100 GeneticVariation disease GWASCAT Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. 28604728 2017
Entrez Id: 7216
Gene Symbol: TRO
TRO 		0.010 Biomarker disease BEFREE These results suggest strongly that trophinin enhances invasiveness of the cells and promotes metastasis of testicular germ cell tumor. 15205339 2004
Entrez Id: 54765
Gene Symbol: TRIM44
TRIM44 		0.010 Biomarker disease BEFREE We aimed to investigate the clinical significance of TRIM44 and its function in TGCT. 27754579 2017
Entrez Id: 7186
Gene Symbol: TRAF2
TRAF2 		0.010 AlteredExpression disease BEFREE Loss of miR-514a-3p expression in TGCT increases PEG3 expression that recruits TRAF2 and activates the NF-kappa B pathway, which protects germ cells from apoptosis. 28471449 2017
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.010 Biomarker disease BEFREE Cytokeratin 7, inhibin, and p63 in testicular germ cell tumor: superior markers of choriocarcinoma compared to β-human chorionic gonadotropin. 30359635 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.060 AlteredExpression disease BEFREE Our results suggest a lack of correlation between cisplatin-induced apoptosis, p53 status and expression of Bcl-2 family proteins in our panel of TGCT cell lines. 9389577 1997