Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 183
Gene Symbol: AGT
AGT
0.090 Biomarker disease BEFREE Endothelial-to-mesenchymal transition (EndMT) is a mechanism that promotes cardiac fibrosis induced by Angiotensin II (AngII). 29073623 2018
Entrez Id: 183
Gene Symbol: AGT
AGT
0.090 AlteredExpression disease BEFREE Osteopontin is indispensible for AP1-mediated angiotensin II-related miR-21 transcription during cardiac fibrosis. 25898844 2016
Entrez Id: 183
Gene Symbol: AGT
AGT
0.090 Biomarker disease BEFREE Cardiac fibrosis and cardiomyocyte hypertrophy were simulated by 100 nM angiotensin II (Ang II) in vitro. 25633415 2015
Entrez Id: 183
Gene Symbol: AGT
AGT
0.090 Biomarker disease BEFREE miR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-β/Smad3 signaling. 24569834 2015
Entrez Id: 183
Gene Symbol: AGT
AGT
0.090 Biomarker disease BEFREE Treatment with anti-IL-16 neutralizing antibody ameliorated cardiac fibrosis in the mouse model of angiotensin II-induced hypertension. 23894370 2014
Entrez Id: 183
Gene Symbol: AGT
AGT
0.090 Biomarker disease BEFREE TNF receptor 1 signaling is critically involved in mediating angiotensin-II-induced cardiac fibrosis. 23337087 2013
Entrez Id: 183
Gene Symbol: AGT
AGT
0.090 AlteredExpression disease BEFREE In cardiac fibroblasts and rats treated with angiotensin II, berberine was found to suppress fibroblast activation, collagen synthesis, and extent of cardiac fibrosis through up-regulating relaxin. 22673230 2012
Entrez Id: 183
Gene Symbol: AGT
AGT
0.090 Biomarker disease BEFREE C-reactive protein promotes cardiac fibrosis and inflammation in angiotensin II-induced hypertensive cardiac disease. 20157054 2010
Entrez Id: 183
Gene Symbol: AGT
AGT
0.090 PosttranslationalModification disease BEFREE Angiotensin II stimulates cardiac fibrosis and conduction heterogeneity. 19648063 2010