Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.230 Biomarker disease BEFREE Endothelin-1 (ET-1) is involved in the pathogenesis of cardiac fibrosis. 28713274 2017
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.230 AlteredExpression disease BEFREE These observations in mice and human hearts suggest that aging-related cardiac fibrosis is, at least partially, dependent on the upregulation of ET-1. 25584774 2015
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.230 Biomarker disease BEFREE These results provide new insights suggesting that diabetes mellitus-induced cardiac fibrosis is associated with the emergence of fibroblasts from endothelial cells and that this endothelial-to-mesenchymal transition process is stimulated by ET-1. 20497976 2010
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.230 Therapeutic disease RGD Effects of cilnidipine on nitric oxide and endothelin-1 expression and extracellular signal-regulated kinase in hypertensive rats. 11430925 2001