Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
0.030 Biomarker disease BEFREE Irisin attenuates angiotensin II-induced cardiac fibrosis via Nrf2 mediated inhibition of ROS/ TGFβ1/Smad2/3 signaling axis. 30703374 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
0.030 Biomarker disease BEFREE Moreover, pretreating CFs with siRNA for Smad7 or Nrf2 both partially reversed the inhibition of AA on Ang II-induced cardiac fibrosis. 31254954 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
0.030 AlteredExpression disease BEFREE Together, these results suggest that puerarin prevents cardiac fibrosis via activation of Nrf2 and inactivation of p38-MAPK. 29928229 2018