Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.360 Biomarker disease CTD_human A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. 29394407 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.360 Biomarker disease BEFREE This study intended to explore the effect of β-catenin on oxidative damage of DCM by establishing streptozotocin (STZ)-induced diabetic mouse model and hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-treated myocardial cell model. 28989026 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.360 Biomarker disease BEFREE Our data demonstrated that canonical Wnt/β-catenin signaling was activated through nuclear accumulation of β-catenin in idiopathic dilated cardiomyopathy, ischemic heart disease, and murine desmin-related cardiomyopathy when compared with nonfailing controls and transcription factor 7-like 2 (TCF7L2) was the main β-catenin partner of the T-cell factor (TCF) family in adult hearts. 27301468 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.360 AlteredExpression disease BEFREE Furthermore, expressions of FAT1 and β-catenin were correlated with each other in DCIS and IDC (P<0.05). 26721716 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.360 GeneticVariation disease BEFREE In support of this hypothesis, we have investigated the ultrastructure of the ID in mouse hearts from control and dilated cardiomyopathy (DCM) models, the MLP-null and a cardiac-specific β-catenin mutant, cΔex3, as well as in human left ventricle from normal and DCM samples. 23708682 2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.360 Biomarker disease BEFREE Association of nuclear Dvl and beta-catenin with vimentin expression suggests the importance of Wnt/beta-catenin pathway driven EMT in IDCs. 18662704 2008
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.360 AlteredExpression disease BEFREE Analysis of tissue sections with similar rates of EC degeneration in both patient groups showed that VE-cadherin/beta-catenin expression was downregulated in DCM only (P<0.05). 12963640 2003