Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.010 Biomarker phenotype BEFREE Data from <sup>18</sup>F-FDG PET/CT studies showed that standardised uptake value (SUV) is significantly associated with the aggressiveness, treatment response and prognosis of this disease. 31392480 2020
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
0.010 Biomarker phenotype BEFREE Cotransfection assays using A549 and H1975 cells future implied that downexpression of TIMP2 rescued the aggressiveness phenotypes of NSCLC cell inhibited by FENDRR. 31545237 2019
Entrez Id: 406999
Gene Symbol: MIR217
MIR217
0.010 AlteredExpression phenotype BEFREE Altogether, upregulation of miR-217 inhibits the aggressiveness phenotypes of cervical carcinoma cell via regulating <i>KRAS</i> gene and increases the sensitivity of cervical cancer cell to cisplatin. 30774364 2019
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
0.010 AlteredExpression phenotype BEFREE There were no differences in the expression of CTR, neither GR in mononucleated stromal cells (MSCs) or multinucleated giant cells (MGCs), in relation to aggressiveness, treatment performed for and the response to conservative treatment. 30028524 2018
Entrez Id: 799
Gene Symbol: CALCR
CALCR
0.010 AlteredExpression phenotype BEFREE There were no differences in the expression of CTR, neither GR in mononucleated stromal cells (MSCs) or multinucleated giant cells (MGCs), in relation to aggressiveness, treatment performed for and the response to conservative treatment. 30028524 2018
Entrez Id: 7468
Gene Symbol: NSD2
NSD2
0.010 AlteredExpression phenotype BEFREE Histone lysine methyltransferase NSD2 was frequently overexpressed in multiple types of cancer such as multiple myeloma, stomach and colon cancer, and the overexpression of it usually associated with aggressiveness tumor type. 28338204 2017
Entrez Id: 831
Gene Symbol: CAST
CAST
0.010 Biomarker phenotype BEFREE The contribution of CAPNs and regulatory calpastatin (CAST) and ERK1/2 kinases to aggressiveness, disease course, and outcome in laryngeal cancer remains elusive. 27456359 2016
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
0.010 Biomarker phenotype BEFREE The contribution of CAPNs and regulatory calpastatin (CAST) and ERK1/2 kinases to aggressiveness, disease course, and outcome in laryngeal cancer remains elusive. 27456359 2016
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
0.010 GeneticVariation phenotype BEFREE In order to relate HLA-DRB1 alleles to disease aggressiveness, patients with relapsing remitting MS and secondary progressive MS were subdivided into 3 groups: 'benign' MS patients who maintain an Extended Disability Status Scale (EDSS) score of <or=3 at least 10 years after disease onset; non-benign MS patients with EDSS>3 after the same period and 'aggressive' MS those with EDSS>or=6 within 15 years of disease onset. 17412364 2007
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
0.010 AlteredExpression phenotype BEFREE Northern blot analysis showed that levels of TIMP-1 mRNAs correlated directly with clinical aggressiveness: tumors in the high-grade category contained the highest levels of TIMP-1 transcripts approaching those found in maximally growth factor-stimulated fibroblasts in vitro. 1645604 1991