×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
Biomarker
group
BEFREE
In both cell lines and primary patient samples, we observed consistent expression patterns of these biomarkers varies by cancer indication, such that ERBB3 and CDKN1B expression are relatively high in breast tumors while EGFR expression is relatively high in other indications.
27035903
2016
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
AlteredExpression
group
BEFREE
The correlation between p27KIP1 expression and rapamycin antitumor activity was also observed in the patient-derived breast tumor xenograft models.
25744729
2015
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
Biomarker
group
BEFREE
Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1 ).
24457952
2014
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
AlteredExpression
group
BEFREE
High Cks1 expression is associated with aggressive breast tumors and correlates with low p27Kip1 levels in some cases, although it is also an independent prognostic marker for survival, and provides predictive information in addition to that provided by p27Kip1 alone.
19360356
2009
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
Biomarker
group
LHGDN
MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1.
18708351
2008
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
Biomarker
group
LHGDN
Polymorphisms cMyc-N11S and p27-V109G and breast cancer risk and prognosis.
17567920
2007
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
AlteredExpression
group
LHGDN
PKCtheta promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor alpha synthesis.
18037997
2007
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
Biomarker
group
LHGDN
Genetic screening reveals an essential role of p27kip1 in restriction of breast cancer progression.
17804714
2007
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
GeneticVariation
group
LHGDN
Variant genotypes of CDKN1A and CDKN1B are associated with an increased risk of breast cancer in Chinese women.
16804901
2006
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
AlteredExpression
group
LHGDN
p27(Kip1) and cyclin E expression and breast cancer survival after treatment with adjuvant chemotherapy.
17148774
2006
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
Biomarker
group
CTD_human
Downregulation of the cyclin-dependent kinase inhibitor p27kip1 might correlate with poor disease-free and overall survival in inflammatory breast cancer.
17092400
2006
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
AlteredExpression
group
LHGDN
Prognostic impact of Skp2 and p27 in human breast cancer.
16636894
2006
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
Biomarker
group
LHGDN
TNFalpha resistance in MCF-7 breast cancer cells is associated with altered subcellular localization of p21CIP1 and p27KIP1.
15592362
2005
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
GeneticVariation
group
LHGDN
Molecular analysis of the p27/kip1 gene in breast cancer.
16035731
2005
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
GeneticVariation
group
LHGDN
Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.
15996662
2005
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
AlteredExpression
group
LHGDN
Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer.
14654548
2003
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
AlteredExpression
group
LHGDN
Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway.
12904306
2003
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
PosttranslationalModification
group
LHGDN
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.
12244303
2002
×
Entrez Id:
1027
Gene Symbol:
CDKN1B
CDKN1B
0.400
AlteredExpression
group
LHGDN
PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.
12244302
2002