Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 AlteredExpression group BEFREE Macrophages attenuate the transcription of CYP1A1 in breast tumor cells and enhance their proliferation. 30615637 2019
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 AlteredExpression group BEFREE In conclusion, PAIB-SOs are novel chemotherapeutic prodrugs with no equivalent among current antineoplastics and whose selective action toward breast cancer is tailored to the characteristic pattern of CYP1A1 expression observed in a large percentage of human breast tumors. 28535350 2017
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 AlteredExpression group BEFREE Semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR) and western-blotting were used to investigate the expression of CYP1A1 in breast cancer control and disease samples. mRNA expression of CYP1A1 was down- regulated in 40% of breast tumor samples. 22901117 2012
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 GeneticVariation group LHGDN Comparative analysis of SNP in estrogen-metabolizing enzymes for ovarian, endometrial, and breast cancers in Novosibirsk, Russia. 18497059 2008
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 GeneticVariation group LHGDN Polymorphisms in genes involved in sex hormone metabolism, estrogen plus progestin hormone therapy use, and risk of postmenopausal breast cancer. 18628428 2008
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 Biomarker group LHGDN Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites. 17919675 2008
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 GeneticVariation group LHGDN Cytochrome P450 1A1 (CYP1A1) T3801C and A2455G polymorphisms in breast cancer risk: a meta-analysis. 17427032 2007
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 AlteredExpression group LHGDN The effect of indole-3-carbinol on the expression of CYP1A1, CYP1B1 and AhR genes and proliferation of MCF-7 cells. 17311112 2007
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 GeneticVariation group LHGDN A study on the association of cytochrome-P450 1A1 polymorphism and breast cancer risk in north Indian women. 16807674 2007
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 GeneticVariation group LHGDN Cytochrome P450 1A1 (CYP1A1) polymorphisms and breast cancer risk in Korean women. 17603290 2007
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 GeneticVariation group LHGDN Association of CYP1A1 polymorphisms with breast cancer in North Indian women. 18351133 2007
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 GeneticVariation group LHGDN Joint effects of the CYP1A1 MspI, ERalpha PvuII, and ERalpha XbaI polymorphisms on the risk of breast cancer: results from a population-based case-control study in Shanghai, China. 16492926 2006
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 Biomarker group CTD_human [Study on serum organochlorines pesticides (DDTs) level, CYP1A1 genetic polymorphism and risk of breast cancer: a case control study]. 16792888 2006
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 GeneticVariation group LHGDN Cytochrome P-450 1A1 gene polymorphisms and risk of breast cancer: a HuGE review. 15870154 2005
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 AlteredExpression group BEFREE The increase in CYP1A1 mRNA in the aminoflavone-sensitive MCF-7 breast tumor cell results from transcriptional activation of xenobiotic-responsive element (XRE)-controlled transcription. 15210858 2004
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 GeneticVariation group LHGDN Associations between breast cancer susceptibility gene polymorphisms and clinicopathological features. 14734460 2004
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 Biomarker group BEFREE Only four CYPs were detected in breast tumor or adjacent tissue: CYP1A1, CYPB1, CYP2C9, CYP3A4. 14703066 2003
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 AlteredExpression group LHGDN Cytochrome p450 and glutathione transferase expression in human breast cancer. 12738724 2003
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 GeneticVariation group LHGDN Aromatic DNA adducts and polymorphisms of CYP1A1, NAT2, and GSTM1 in breast cancer. 11872636 2002
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.400 Biomarker group BEFREE Differential regulation of cytochrome P450 1A1 and 1B1 by a combination of dioxin and pesticides in the breast tumor cell line MCF-7. 11358810 2001