Gene: MTHFR ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group BEFREE Subgroup analyses by menopausal status, hormone receptor status of breast tumors (estrogen receptor [ER], progesterone receptor [PR] and human epidermal growth factor receptor 2 [HER2]), alcohol intake and MTHFR polymorphisms (677C > T and 1298A > C) were also performed. 27905104 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group BEFREE DNA promoter methylation in breast tumors: no association with genetic polymorphisms in MTHFR and MTR. 19240236 2009
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN One-carbon metabolism-related gene polymorphisms and risk of breast cancer. 18174236 2008
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN Methionine-dependence phenotype in the de novo pathway in BRCA1 and BRCA2 mutation carriers with and without breast cancer. 18842997 2008
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN Multiple Genetic Polymorphisms of GSTP1 313AG, MDR1 3435CC, and MTHFR 677CC highly correlated with early relapse of breast cancer patients in Taiwan. 18095031 2008
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN GSTP1 and MTHFR polymorphisms are related with toxicity in breast cancer adjuvant anthracycline-based treatment. 17584018 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN Role of MTHFR (677, 1298) haplotype in the risk of developing secondary leukemia after treatment of breast cancer and hematological malignancies. 17476281 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 Biomarker group CTD_human Breast cancer risk associated with multigenotypic polymorphisms in folate-metabolizing genes: a nested case-control study in Taiwan. 17595805 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: a nested-case-control study and a pooled meta-analysis. 17260091 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN Methyl group metabolism gene polymorphisms as modifier of breast cancer risk in Italian BRCA1/2 carriers. 17151928 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 Biomarker group LHGDN No association between methylenetetrahydrofolate reductase C677T polymorphism and breast cancer. 16134079 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN Methylenetetrahydrofolate reductase haplotype tag single-nucleotide polymorphisms and risk of breast cancer. 17119067 2006
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN Genetic polymorphisms of the methylenetetrahydrofolate reductase gene, plasma folate levels and breast cancer susceptibility: a case-control study in Taiwan. 16777985 2006
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 Biomarker group CTD_human Genetic polymorphisms of the methylenetetrahydrofolate reductase gene, plasma folate levels and breast cancer susceptibility: a case-control study in Taiwan. 16777985 2006
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN Homozygosity at the C677T of the MTHFR gene is associated with increased breast cancer risk in the Turkish population. 16097444 2005
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN MTHFR genotypes and breast cancer survival after surgery and chemotherapy: a report from the Shanghai Breast Cancer Study. 15868433 2005
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN Methylenetetrahydrofolate reductase and thymidylate synthase polymorphisms are not associated with breast cancer risk or phenotype. 15510613 2004
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.400 GeneticVariation group LHGDN Polymorphisms in the MTHFR gene are associated with breast cancer. 15004488 2004