Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.090 | AlteredExpression | phenotype | BEFREE | These findings suggest MUC1 is a critical regulator of PD-L1 expression via its effects on microRNA levels and represents a potential therapeutic target to enhance anti-tumor immunity. | 28555079 | 2017 | ||||
|
0.090 | Biomarker | phenotype | BEFREE | MUC1 and maltose‑binding protein recombinant fusion protein combined with Bacillus Calmette‑Guerin induces MUC1‑specific and nonspecific anti‑tumor immunity in mice. | 24912810 | 2014 | ||||
|
0.090 | Biomarker | phenotype | BEFREE | MF59 formulated with CpG ODN as a potent adjuvant of recombinant HSP65-MUC1 for inducing anti-MUC1+ tumor immunity in mice. | 22595192 | 2012 | ||||
|
0.090 | AlteredExpression | phenotype | BEFREE | We suggest that effective immunotherapy with autologous MUC1-stimulated CD4(+) effector cells induces differential levels of systemic "Ag-experienced" and "Ag-inexperienced" CD4/CD25(+) TReg cell subpopulations that influence long-term tumor immunity in ovarian cancer patients. | 19762283 | 2009 | ||||
|
0.090 | AlteredExpression | phenotype | BEFREE | MUC-1 mucin is an epithelial cell antigen whose aberrant expression plays a role in autoimmunity and tumor immunity in the majority of human carcinomas and multiple myeloma. | 18158739 | 2007 | ||||
|
0.090 | Biomarker | phenotype | BEFREE | In addition, aberrant glycosylation of MUC-1 on human tumors leads to exposure of cryptic peptide epitopes that play a role in tumor immunity. | 15076142 | 2004 | ||||
|
0.090 | Biomarker | phenotype | BEFREE | TCR-alpha/beta(+) cells were required to eliminate Panc02.MUC1 tumors, while TCR-gamma/delta(+) cells played a suppressive non-MUC1-specific role in anti-Panc02 tumor immunity. | 12111121 | 2002 | ||||
|
0.090 | Biomarker | phenotype | BEFREE | Tumor immunity specific for MUC1 was produced in wild-type mice by two different procedures: (i) s.c. immunization of wild-type mice with a low dose of Panc02-MUC1 or (ii) adoptive transfer of spleen and lymph node cells harvested from wild-type mice previously immunized s.c. with Panc02-MUC1. | 11157856 | 2001 | ||||
|
0.090 | Biomarker | phenotype | BEFREE | Tumor immunity in vivo was characterized by an adoptive transfer method to evaluate the degree of MUC1 or non-MUC1 tumor immunity in wt or MUC1.Tg mice. | 9820526 | 1998 |