Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.080 Biomarker phenotype BEFREE Forkhead box p3 (Foxp3<sup>+</sup>) regulatory T cells (Tregs) are abundant in the tumor microenvironment where they dampen functions of host anti-tumor immunity and promote cancer progression. 31062086 2019
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.080 Biomarker phenotype BEFREE Foxp3-expressing regulatory T (Treg) cells, which are indispensable for preventing autoimmunity, also suppress effective tumor immunity. 31257581 2019
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.080 AlteredExpression phenotype BEFREE Regulatory T cells (Tregs) are CD4+ T cells that express CD25 and transcription factor Forkhead box P3 (FOXP3), and Tregs play a central role in regulation of tumor immunity. 30502715 2019
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.080 Biomarker phenotype BEFREE FOXP3+ Treg as a therapeutic target for promoting anti-tumor immunity. 29532697 2018
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.080 AlteredExpression phenotype BEFREE Regulatory T (Treg) cells expressing the transcription factor Foxp3 are critical for the prevention of autoimmunity and the suppression of anti-tumor immunity. 28709804 2017
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.080 GeneticVariation phenotype BEFREE Therefore, it is crucial to investigate the "true Treg (eTreg)" population, rather than the entire FOXP3 population, with regards to their effect on tumor immunity. 29296965 2017
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.080 AlteredExpression phenotype BEFREE FoxP3 expression is a marker for Tregs which are known to be involved in tumor immunity. 24291052 2014
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.080 Biomarker phenotype BEFREE CD4+ CD25+ forkhead box P3 (FOXP3)+ T(reg) accumulate in malignant tumors and negatively regulate anti-tumor immunity. 17928188 2008