Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
0.040 Biomarker phenotype BEFREE However, whether SHP099-mediated SHP2 inhibition retards tumor growth <i>in vivo via</i> anti-tumor immunity remains elusive. 30972278 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
0.040 Biomarker phenotype BEFREE The Src homology 2 domain-containing protein tyrosine phosphatase 2 (Shp2) is generally considered to be an oncogene owing to its ability in enhancing the malignancy of multiple types of tumor cells; however, its role in modulating tumor immunity remains largely elusive. 29795405 2018
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
0.040 Biomarker phenotype BEFREE T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice. 27935860 2017
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
0.040 Biomarker phenotype BEFREE However, the role of SHP-2 in tumor immunity remains unclear. 24088816 2013