Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.010 Biomarker phenotype LHGDN Plasmatic B-type natriuretic peptide and C-reactive protein in hyperacute stroke as markers of CT-evidence of brain edema. 18219371 2008
Entrez Id: 23657
Gene Symbol: SLC7A11
SLC7A11 		0.010 Biomarker phenotype LHGDN Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema. 18469825 2008
Entrez Id: 4879
Gene Symbol: NPPB
NPPB 		0.010 Biomarker phenotype LHGDN Plasmatic B-type natriuretic peptide and C-reactive protein in hyperacute stroke as markers of CT-evidence of brain edema. 18219371 2008
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.010 Biomarker phenotype LHGDN These results suggest that ET-1 may be a new diagnostic marker for development of severe brain edema in patients with acute ischemic stroke treated with t-PA. 18436890 2008
Entrez Id: 773
Gene Symbol: CACNA1A
CACNA1A 		0.010 GeneticVariation phenotype LHGDN Specific kinetic alterations of human CaV2.1 calcium channels produced by mutation S218L causing familial hemiplegic migraine and delayed cerebral edema and coma after minor head trauma. 15743764 2005
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.200 Biomarker phenotype RGD Time course of Keap1-Nrf2 pathway expression after experimental intracerebral haemorrhage: correlation with brain oedema and neurological deficit. 23438812 2013
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8 		0.200 Therapeutic phenotype RGD Inhibition of SUR1 decreases the vascular permeability of cerebral metastases. 23633925 2013
Entrez Id: 3606
Gene Symbol: IL18
IL18 		0.200 Therapeutic phenotype RGD Interleukin-18 attenuates disruption of brain-blood barrier induced by status epilepticus within the rat piriform cortex in interferon-γ independent pathway. 22338606 2012
Entrez Id: 1756
Gene Symbol: DMD
DMD 		0.200 Biomarker phenotype RGD Interleukin-18 attenuates disruption of brain-blood barrier induced by status epilepticus within the rat piriform cortex in interferon-γ independent pathway. 22338606 2012
Entrez Id: 358
Gene Symbol: AQP1
AQP1 		0.200 Biomarker phenotype RGD [Changes of VEGF and AQPs gene and protein expression in rat brain tissue during hypoxic encephaledema]. 21560328 2011
Entrez Id: 2147
Gene Symbol: F2
F2 		0.200 Biomarker phenotype RGD Time course of upregulation of inflammatory mediators in the hemorrhagic brain in rats: correlation with brain edema. 20541575 2010
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.200 Biomarker phenotype RGD The effects of Tanshinone IIA on blood-brain barrier and brain edema after transient middle cerebral artery occlusion in rats. 20570121 2010
Entrez Id: 2149
Gene Symbol: F2R
F2R 		0.200 Biomarker phenotype RGD Time course of upregulation of inflammatory mediators in the hemorrhagic brain in rats: correlation with brain edema. 20541575 2010
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		0.200 Biomarker phenotype RGD Temporal profiles of aquaporin 4 expression and astrocyte response in the process of brain damage in fat embolism model in rats. 20111877 2010
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2 		0.200 Biomarker phenotype RGD These results suggest that MIP-2 expression may play an important role in the development of brain edema after ICH in rats. 18830379 2009
Entrez Id: 5270
Gene Symbol: SERPINE2
SERPINE2 		0.200 Biomarker phenotype RGD Our studies were designed to investigate the regulation and distribution of protease nexin-1 (PN-1), thrombin and aquaporin-4 (AQP-4) in brain edema after ICH in rat and human brain in vivo. 18442833 2008
Entrez Id: 5327
Gene Symbol: PLAT
PLAT 		0.200 Biomarker phenotype RGD Blood brain barrier (BBB) dysfunction associated with increased expression of tissue and urokinase plasminogen activators following peripheral thermal injury. 18718505 2008
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8 		0.200 Biomarker phenotype RGD Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke. 16550187 2006
Entrez Id: 552
Gene Symbol: AVPR1A
AVPR1A 		0.200 Biomarker phenotype RGD Protective effect of the V1a receptor antagonist SR49059 on brain edema formation following middle cerebral artery occlusion in the rat. 16671476 2006
Entrez Id: 1356
Gene Symbol: CP
CP 		0.200 Biomarker phenotype RGD In the second set of experiments, rats received either ferric iron, ferrous iron, or ferrous iron plus ceruloplasmin, then were killed 24 hours later for brain edema measurement. 16671455 2006
Entrez Id: 727
Gene Symbol: C5
C5 		0.200 Biomarker phenotype RGD Systemic complement depletion diminishes perihematomal brain edema in rats. 11136932 2001
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.220 Biomarker phenotype RGD [Changes of VEGF and AQPs gene and protein expression in rat brain tissue during hypoxic encephaledema]. 21560328 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.220 AlteredExpression phenotype LHGDN Expression of vascular endothelial growth factor-A and mRNA stability factor HuR in human meningiomas. 18317686 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.220 Biomarker phenotype RGD Vascular endothelial growth factor antagonist reduces brain edema formation and venous infarction. 15879344 2005
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.220 AlteredExpression phenotype LHGDN [Correlation between vascular endothelial growth factor and peritumoural edema in meningiomas]. 12425822 2002