Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.060 GeneticVariation disease BEFREE Mutation of the KRAS oncogene is common in typical pancreatic duct adenocarcinoma. 9013836 1997
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.060 GeneticVariation disease BEFREE Negative staining for pan-ras, H-ras, and N-ras in cases with wild-type K-ras genes suggests that alternative routes of ras gene alteration are not operative in IPMT or ductal carcinoma. 10374765 1999
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.060 Biomarker disease BEFREE In the past two decades, multiple studies have revealed that SMAD4 loss on its own does not initiate tumor formation, but can promote tumor progression initiated by other genes, such as KRAS activation in pancreatic duct adenocarcinoma and APC inactivation in colorectal cancer. 29483830 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.060 GeneticVariation disease BEFREE Twelve of thirteen cases (92%) of intraductal papillary mucinous tumor of the pancreas, confirmed histologically (9 adenomas and 4 carcinomas), and 26 of 43 cases (60%) of ductal carcinoma showed specific K-ras gene mutations in the pancreatic juice. 9041151 1997
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.060 GeneticVariation disease BEFREE Mutations on the KRAS gene occur early during pancreatic duct cell carcinogenesis and have been identified in up to 90% of ductal adenocarcinoma. 18374152 2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.060 Biomarker disease BEFREE The role of KRAS copy number changes and resulting KRAS mutant allele-specific imbalance (MASI) in ductal adenocarcinoma (n=94), and its progression into undifferentiated carcinoma of the pancreas (n=25) was studied by direct sequencing and KRAS fluorescence in situ hybridization (FISH). 23599154 2013