Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 24147
Gene Symbol: FJX1
FJX1 		0.300 Biomarker group CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		0.300 Biomarker group CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 10788
Gene Symbol: IQGAP2
IQGAP2 		0.300 Biomarker group CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 8826
Gene Symbol: IQGAP1
IQGAP1 		0.300 Biomarker group CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 154796
Gene Symbol: AMOT
AMOT 		0.300 Biomarker group CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.300 Biomarker group CTD_human Resveratrol Targeting of Carcinogen-Induced Brain Endothelial Cell Inflammation Biomarkers MMP-9 and COX-2 is Sirt1-Independent. 22523472 2012
Entrez Id: 5970
Gene Symbol: RELA
RELA 		0.300 Biomarker group CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960 2011
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Biomarker group CTD_human Hydrogen peroxide contributes to the manganese superoxide dismutase promotion of migration and invasion in glioma cells. 21749277 2011
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		0.300 Biomarker group CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960 2011
Entrez Id: 5111
Gene Symbol: PCNA
PCNA 		0.300 Biomarker group CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960 2011
Entrez Id: 113878
Gene Symbol: DTX2
DTX2 		0.300 Biomarker group CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 28514
Gene Symbol: DLL1
DLL1 		0.300 Biomarker group CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 441478
Gene Symbol: NRARP
NRARP 		0.300 Biomarker group CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 388585
Gene Symbol: HES5
HES5 		0.300 Biomarker group CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.300 Biomarker group CTD_human MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma. 20131314 2010
Entrez Id: 1612
Gene Symbol: DAPK1
DAPK1 		0.300 Biomarker group CTD_human DAPK1 promoter hypermethylaiton in brain metastases and peripheral blood. 17319784 2007
Entrez Id: 6696
Gene Symbol: SPP1
SPP1 		0.300 Biomarker group CTD_human Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea. 16651633 2006
Entrez Id: 5444
Gene Symbol: PON1
PON1 		0.300 Biomarker group CTD_human Risk of brain tumors in children and susceptibility to organophosphorus insecticides: the potential role of paraoxonase (PON1). 16002382 2005
Entrez Id: 7052
Gene Symbol: TGM2
TGM2 		0.300 Therapeutic group CTD_human Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas. 16170020 2005
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.300 Biomarker group CTD_human Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. 9581815 1998
Entrez Id: 6608
Gene Symbol: SMO
SMO 		0.300 Biomarker group CTD_human Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. 9581815 1998
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.200 Biomarker group CTD_mouse Evaluation of genetic alterations in cancer-related genes in lung and brain tumors from B6C3F1 mice exposed to 1,3-butadiene or chloroprene. 16860786 2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.070 AlteredExpression group BEFREE Quantitative multi-parametric magnetic resonance imaging analyses indicated increased tumor invasion for EGFR<sup>A289D/T/V</sup> mutants, corroborated in mice bearing intracranial tumors expressing EGFR<sup>A289V</sup> and dependent on ERK-mediated expression of matrix metalloproteinase-1. 29990498 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.070 Biomarker group BEFREE This comprehensive dataset provides simultaneous insight into pharmacokinetics and pharmacodynamics and indicates that erlotinib delivery to intracranial tumors is insufficient to inhibit EGFR tyrosine kinase signaling. 30464169 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.070 Biomarker group BEFREE As such, ARMS-PCR could play an important role in guiding EGFR-tyrosine kinase inhibitor treatments of intracranial tumors and for diagnosing brain metastases in patients with lung adenocarcinoma. 24994671 2014