Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2022
Gene Symbol: ENG
ENG
0.300 Biomarker disease CTD_human CFTR dysfunction increases endoglin and TGF-β signaling in airway epithelia. 30806029 2019
Entrez Id: 51164
Gene Symbol: DCTN4
DCTN4
0.300 Biomarker disease CTD_human Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis. 22772370 2012
Entrez Id: 6337
Gene Symbol: SCNN1A
SCNN1A
0.300 Biomarker disease CTD_human Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease. 19462466 2009
Entrez Id: 6338
Gene Symbol: SCNN1B
SCNN1B
0.300 Biomarker disease CTD_human The TNFalpha receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis. 16463024 2006
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
0.300 Biomarker disease CTD_human The TNFalpha receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis. 16463024 2006
Entrez Id: 6340
Gene Symbol: SCNN1G
SCNN1G
0.300 Biomarker disease CTD_human The TNFalpha receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis. 16463024 2006
Entrez Id: 6338
Gene Symbol: SCNN1B
SCNN1B
0.300 Biomarker disease CTD_human Mutations in the beta-subunit of the epithelial Na+ channel in patients with a cystic fibrosis-like syndrome. 16207733 2005
Entrez Id: 6337
Gene Symbol: SCNN1A
SCNN1A
0.300 Biomarker disease CTD_human Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice. 15077107 2004
Entrez Id: 2212
Gene Symbol: FCGR2A
FCGR2A
0.300 Biomarker disease CTD_human
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.300 Biomarker disease CTD_human
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease BEFREE Cystic Fibrosis of the Pancreas: The Role of CFTR Channel in the Regulation of Intracellular Ca<sup>2+</sup> Signaling and Mitochondrial Function in the Exocrine Pancreas. 30618777 2018
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human Cystic fibrosis transmembrane regulator potentiators as promising cystic fibrosis therapies. 21303308 2011
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human Probing conformational rescue induced by a chemical corrector of F508del-cystic fibrosis transmembrane conductance regulator (CFTR) mutant. 21602569 2011
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation. 21083385 2010
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. 19309154 2009
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770. 19846789 2009
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human Proteasome-dependent pharmacological rescue of cystic fibrosis transmembrane conductance regulator revealed by mutation of glycine 622. 18230692 2008
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease BEFREE CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector. 17654517 2008
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human Restoration of W1282X CFTR activity by enhanced expression. 17541014 2007
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human No detectable improvements in cystic fibrosis transmembrane conductance regulator by nasal aminoglycosides in patients with cystic fibrosis with stop mutations. 17347447 2007
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin. 17290305 2007
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human The TNFalpha receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis. 16463024 2006
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human Cystic fibrosis in 65- and 67-year-old siblings. Clinical feature and nasal potential difference measurement in patients with genotypes F508del and 2789+5G-->A. 16763370 2006
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease BEFREE Expression of a wild-type CFTR maintains the integrity of the biosynthetic/secretory pathway in human cystic fibrosis pancreatic duct cells. 15956032 2005
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
0.330 Biomarker disease CTD_human Correction of CFTR malfunction and stimulation of Ca-activated Cl channels restore HCO3- secretion in cystic fibrosis bile ductular cells. 11786964 2002