Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 GeneticVariation disease BEFREE CYP2C19 genotype-guided antiplatelet therapy in ST-segment elevation myocardial infarction patients-Rationale and design of the Patient Outcome after primary PCI (POPular) Genetics study. 24952855 2014
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Utility of post-procedural anticoagulation after primary PCI for STEMI: insights from a pooled analysis of the HORIZONS-AMI and EUROMAX trials. 27287251 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Update on primary PCI for patients with STEMI. 27450063 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Increased PLR levels are independently associated with a greater risk of CI-AKI in patients undergoing primary PCI for STEMI. 27473864 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Despite primary PCI being the well-established therapy, there are rooms for further research to optimize STEMI outcomes. 27846459 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 GeneticVariation disease BEFREE Low risk patients identified using CADILLAC risk score with STEMI treated successfully with primary PCI have a low adverse event rate on the third day or later of hospitalization suggesting that an earlier discharge is safe in properly selected patients. 27896906 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE In conclusion, prasugrel and ticagrelor decreased the risk of all-cause death, major adverse cardiac events, and stent thrombosis without causing more bleeding events compared with clopidogrel in patients with STEMI undergoing PCI. 28045759 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE During the same time period, eight consecutive patients with large anterior STEMI who received primary PCI but not HT were included as control group. 28087172 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE The influence of polymorphisms in the large group of MMP and TIMP genes on clinical outcomes in patients after ST elevation myocardial infarction (STEMI) treated with primary PCI was analysed. 28101856 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE From 2007 to 2014, 1,525 consecutive patients (79% men, mean age 61 years) who underwent primary percutaneous coronary intervention for STEMI in the INTERSTELLAR (Incheon-Bucheon Cohort of Patients Undergoing Primary PCI for Acute ST-Elevation Myocardial Infarction) cohort were analyzed retrospectively. 28214004 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 GeneticVariation disease BEFREE Door-to-balloon (DTB) time ≤90 min is an important quality indicator in the management of ST-elevation myocardial infarction (STEMI), but a considerable number of patients still do not meet this goal, particularly in countries outside the USA and Europe.Methods and Results:We analyzed 2,428 STEMI patients who underwent primary PCI ≤12 h of symptom onset who were registered in an ongoing prospective multicenter database (JCD-KiCS registry), between 2008 and 2013. 28228609 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Antithrombotic therapy for patients with STEMI undergoing primary PCI. 28230176 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Impact of point-of-care pre-procedure creatinine and eGFR testing in patients with ST segment elevation myocardial infarction undergoing primary PCI: The pilot STATCREAT study. 28400120 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE In the DANAMI-3-PRIMULTI study (Primary PCI in Patients With ST-Elevation Myocardial Infarction and Multivessel Disease: Treatment of Culprit Lesion Only or Complete Revascularization), we randomized 627 ST-segment-elevation myocardial infarction patients to fractional flow reserve-guided complete revascularization or infarct-related percutaneous coronary intervention only. 28404623 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE All patients in group 1 underwent elective angioplasty and stenting, whereas all patients included in groups 2 and 3 suffered from acute coronary syndromes (STEMI or NSTEMI) and underwent urgent PCI. 28425039 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE In patients with STEMI and LV dysfunction doxycycline can favorably modulate the LV filling pattern early after primary PCI. 28433557 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Fewer diabetic patients met first medical contact to PCI time for STEMI (44% vs 52%). 28454811 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Emergent or urgent CABG for treatment of acute coronary complications following PCI is feasible and has acceptable clinical results that worsen in the presence of STEMI, cardiogenic shock, or resuscitation. 28457342 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Numbers of PCIs have risen by 15% over the last four years, coinciding with an increase in the number of cathlabs by 50%, aiming at better access to primary PCI for STEMI patients. 28504223 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE The records were reviewed for patients admitted to the large comprehensive university hospital for PCI due to STEMI from January 1, 2002 to January 1, 2017. 28511806 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Reloaded patients were younger, had fewer comorbid conditions, and were more likely to be treated with primary PCI (STEMI) or an early invasive strategy (NSTEMI). 28541452 2018
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Use of the CADILLIAC Risk Score can accurately identify patients for safe early discharge after PCI for STEMI. 28612413 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE During hospitalization, Patients in prior BBs group were more likely to develop decompensated heart failure (9.9% vs. 3.6%, P<0.001), less likely to have STEMI (33.9% vs. 54.4%, P<0.001), and subsequently less PCI (73.2% vs. 81.3%, P=0.002), but higher inpatient mortality (8.8% vs. 4.8%, P=0.009). 28747039 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE All patients presenting to the Alfred Hospital, a tertiary referral hospital, between 1 January 2010 and 31 December 2015 undergoing PCI for STEMI were identified. 28797607 2018
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Increased hs-CRP levels at presentation are associated with impaired microvascular reperfusion after PCI in STEMI patients and remain higher until 2months follow-up. 28826799 2017