Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE Clinical trials have failed to demonstrate the superiority of pretreatment with P2Y12 inhibitors in ST-segment-elevation myocardial infarction, but they were not designed to assess hard clinical end points. 30354592 2018
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE Pretreatment with P2Y12 inhibitors and outcome in patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention. 29528868 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE To demonstrate the possible association of statin therapy with C reactive protein (CRP) serial measurements in ST elevation myocardial infarction (STEMI) patients. 29620476 2019
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Prognosis and first diagnostic ECG in STEMI patients referred to the emergency medical system for primary PCI. 30497744 2019
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Combined LVEDP/LVEF assessment was useful in predicting MACE after successful PCI for STEMI patients and could facilitate risk stratification, as it predicts LV remodeling. 29143103 2018
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 GeneticVariation disease BEFREE In this single-center prospective randomized study, patients with subacute STEMI presenting ≥12 and ≤48 h after symptom onset were randomized to primary PCI with or without manual TA in a 1:1 ratio. 29869443 2018
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 GeneticVariation disease BEFREE Low risk patients identified using CADILLAC risk score with STEMI treated successfully with primary PCI have a low adverse event rate on the third day or later of hospitalization suggesting that an earlier discharge is safe in properly selected patients. 27896906 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE MHR could be a better parameter than NLR and C-reactive protein at predicting severity of coronary artery disease in STEMI patients treated with pPCI. 29375221 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE Replacement of cross-sectional renal assessment by ΔeGRF and addition of 3 clinical parameters (diabetes, anterior infarct location and C-reactive protein), forming the new ACEF-STEMI score, led to a significant improvement in MACE prediction (AUC:0.75 [95%CI:0.66-0.84]) as compared to original ACEF or ACEF-MDRD (both p = 0.03). 29655951 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE Thirteen patients received two sequential CRP-apheresis treatments with the PentraSorb CRP adsorber starting 24 ± 12 h after STEMI and successful percutaneous coronary intervention (PCI). 30924312 2019
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 GeneticVariation disease BEFREE CYP2C19 genotype-guided antiplatelet therapy in ST-segment elevation myocardial infarction patients-Rationale and design of the Patient Outcome after primary PCI (POPular) Genetics study. 24952855 2014
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE The records were reviewed for patients admitted to the large comprehensive university hospital for PCI due to STEMI from January 1, 2002 to January 1, 2017. 28511806 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE The objective of the current study was to assess the prognostic value of ACEF scores in acute ST-segment elevation myocardial infarction (STEMI) patients with non-IRA CTO after successful primary PCI. 28940388 2018
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE This study aimed to explore the effects of ticagrelor (a P2Y12 receptor inhibitor) on interleukin (IL)-17 and myeloperoxidase (MPO) expression in coronary thrombus as well as on the coronary blood flow in ST-segment elevation myocardial infarction (STEMI) patients following percutaneous coronary intervention (PCI). 29894287 2018
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 GeneticVariation disease BEFREE We chose the acute ST-elevation myocardial infarction (ASTEMI) patients treated with direct PCI to compare different administration routes of diltiazem. 30223281 2018
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Left Ventricular Thrombus After Primary PCI for ST-Elevation Myocardial Infarction: 1-Year Clinical Outcomes. 30871923 2019
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE Pretreatment with P2Y12 inhibitors before primary percutaneous coronary intervention (PPCI) can reduce the incidence of major adverse cardiovascular event (MACE) rate in ST-segment elevation myocardial infarction (STEMI) patients. 30318484 2018
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE We sought to evaluate outcomes on the basis of P2Y12 inhibitor therapy in patients from the Thrombectomy With PCI Versus PCI Alone in Patients With STEMI Undergoing Primary PCI (TOTAL) trial. 31492492 2019
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE There is some surrogate outcome data supporting deferring PCI in STEMI No hard data to support deferring PCI in STEMI No hard data to refute deferring PCI in STEMI Current national quality measures do not offer a method to adequately document appropriateness of deferring PCI. 29405597 2018
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE In the DANAMI-3-PRIMULTI study (Primary PCI in Patients With ST-Elevation Myocardial Infarction and Multivessel Disease: Treatment of Culprit Lesion Only or Complete Revascularization), we randomized 627 ST-segment-elevation myocardial infarction patients to fractional flow reserve-guided complete revascularization or infarct-related percutaneous coronary intervention only. 28404623 2017
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Overall no difference in ventricular rhythm disturbance was seen with intra-coronary nitrite treatment during primary PCI in STEMI patients, however nitrite treatment was associated with an important reduction in the incidence and severity of NSVT. 29887423 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE An hs-TNT Second Peak Associated with High CRP at Day 2 Appears as Potential Biomarkers of Micro-Vascular Occlusion on Magnetic Resonance Imaging after Reperfused ST-Segment Elevation Myocardial Infarction. 30138917 2018
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5
0.100 Biomarker disease BEFREE Numbers of PCIs have risen by 15% over the last four years, coinciding with an increase in the number of cathlabs by 50%, aiming at better access to primary PCI for STEMI patients. 28504223 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 AlteredExpression disease BEFREE The coincidence of Helicobacter pylori-seropositivity and interleukin-1 polymorphisms was significantly associated with higher levels of high sensitivity C-reactive protein and the increased risk of ST-segment elevation myocardial infarction. 27832202 2016
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE High-sensitivity C-reactive protein and long term reperfusion success of primary percutaneous intervention in ST-elevation myocardial infarction. 28826799 2017