We therefore suggest that miR-126, miR-143, miR-145, and miR-223 are potential biomarkers of vascular calcification and cardiovascular disease associated with CKD.
Expression of these vascular miRNAs miR-125b, miR-145, and miR-155 was decreased in the thoracic aorta in CKD rats compared to normal rats, with concordant changes in target genes of RUNX2, angiotensin II type I receptor (AT1R), and myocardin.