Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 92
Gene Symbol: ACVR2A
ACVR2A
0.030 Biomarker group BEFREE We examined activin receptor type IIA (ActRIIA) activation in chronic kidney disease (CKD) by signal analysis and inhibition in mice with Alport syndrome using the ActRIIA ligand trap RAP-011 initiated in 75-day-old Alport mice. 28843411 2018
Entrez Id: 92
Gene Symbol: ACVR2A
ACVR2A
0.030 Biomarker group BEFREE Thus, an ActRIIA ligand trap reversed CKD-stimulated bone remodeling, likely through inhibition of activin-A induced osteoclastogenesis. 27666759 2017
Entrez Id: 92
Gene Symbol: ACVR2A
ACVR2A
0.030 Biomarker group BEFREE Activin A binds to the type 2 activin A receptor, ActRIIA, which is variably affected by CKD in the vasculature. 28119179 2017