Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 28
Gene Symbol: ABO
ABO
0.010 Biomarker disease BEFREE Overweight and obesity modifies the effect of ABO locus on serum ALP concentrations. 24094242 2013
Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
0.010 Biomarker disease BEFREE Incidence of IBD is rising in parallel with overweight and obesity. 27899815 2017
Entrez Id: 84680
Gene Symbol: ACCS
ACCS
0.010 Biomarker disease BEFREE We reviewed the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database from 2008 to 2016 to evaluate the reported 30-day rates of DVT, PE, and combined venous thromboembolism (VTE) after primary THA, primary TKA, revision THA, and revision TKA according to BMI as a continuous variable and a categorical variable as defined by the World Health Organization cutoffs for underweight, normal weight, overweight, and obesity. 30624321 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.010 Biomarker disease BEFREE The associations of 23 SNPs located within 17 candidate genes (MTHFR, PPARγ, LPL, INSIG, TCF7L2, FTO, KCNJ11, JAZF1, CDKN2A/B, ADIPOQ, WFS1, CDKAL1, IGF2BP2, KCNQ1, MTNR1B, IRS1, ACE) with overweight and obesity, diabetes, metabolic phenotypes, and MetS were examined in both studies. 24959828 2014
Entrez Id: 11332
Gene Symbol: ACOT7
ACOT7
0.010 GeneticVariation disease BEFREE Using a series of height and weight assessments from the Australian Capital Territory Physical Activity and Nutrition Survey (ACTPANS), trends in prevalence of overweight and obesity by socioeconomic status were examined in ACT Year 6 school children between 2006 and 2018. 31718605 2019
Entrez Id: 51703
Gene Symbol: ACSL5
ACSL5
0.010 GeneticVariation disease BEFREE Women with overweight and obesity carrying the ACSL5 rs2419621 [T] allele are more responsive to lifestyle interventions in comparison to non-carriers. 27515448 2016
Entrez Id: 55902
Gene Symbol: ACSS2
ACSS2
0.010 Biomarker disease BEFREE We reviewed the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database from 2008 to 2016 to evaluate the reported 30-day rates of DVT, PE, and combined venous thromboembolism (VTE) after primary THA, primary TKA, revision THA, and revision TKA according to BMI as a continuous variable and a categorical variable as defined by the World Health Organization cutoffs for underweight, normal weight, overweight, and obesity. 30624321 2019
Entrez Id: 345651
Gene Symbol: ACTBL2
ACTBL2
0.010 GeneticVariation disease BEFREE Using a series of height and weight assessments from the Australian Capital Territory Physical Activity and Nutrition Survey (ACTPANS), trends in prevalence of overweight and obesity by socioeconomic status were examined in ACT Year 6 school children between 2006 and 2018. 31718605 2019
Entrez Id: 71
Gene Symbol: ACTG1
ACTG1
0.010 GeneticVariation disease BEFREE Using a series of height and weight assessments from the Australian Capital Territory Physical Activity and Nutrition Survey (ACTPANS), trends in prevalence of overweight and obesity by socioeconomic status were examined in ACT Year 6 school children between 2006 and 2018. 31718605 2019
Entrez Id: 72
Gene Symbol: ACTG2
ACTG2
0.010 GeneticVariation disease BEFREE Using a series of height and weight assessments from the Australian Capital Territory Physical Activity and Nutrition Survey (ACTPANS), trends in prevalence of overweight and obesity by socioeconomic status were examined in ACT Year 6 school children between 2006 and 2018. 31718605 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.030 AlteredExpression disease BEFREE The objective of the study was to analyze the association between UCP polymorphisms, clinical parameters and leptin and adiponectin plasma levels in an adolescent population with overweight and obesity. 29634487 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.030 AlteredExpression disease BEFREE Overweight and obesity and adiponectin levels may be useful as markers in HSCT survivors. 28039914 2017
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.030 GeneticVariation disease BEFREE Particularly, gene polymorphisms in ADIPOQ (rs1501299 and rs17300539), LepR (rs1137101 and rs1045895), IRS2 (rs1805092), GRB14 (rs10195252 and rs3923113) and PPARG (rs1801282) have been associated with overweight and obesity in uncontrolled T2DM. 26999420 2016
Entrez Id: 151
Gene Symbol: ADRA2B
ADRA2B
0.010 GeneticVariation disease BEFREE After adjustment for covariates, the ADRA2B DD compared with II homozygotes had significantly (P <or= 0.01) lower BMI (21.9 versus 22.5 kg/m2), waist-to-hip ratio (0.835 versus 0.847), and triceps skinfold thickness (1.18 versus 1.27 cm) and had a significantly lower risk of overweight and obesity (odds ratio 0.52, 95% confidence interval, 0.49-0.54, P=0.0001). 18854756 2008
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3
0.010 GeneticVariation disease BEFREE The results of this study have shown a significant association between the Trp64Arg polymorphism in ADRB3 gene and the development of overweight and obesity in Saudi populations. 29587766 2018
Entrez Id: 64400
Gene Symbol: AKTIP
AKTIP
0.010 AlteredExpression disease BEFREE Lack of association between genetic polymorphism of FTO, AKT1 and AKTIP in childhood overweight and obesity. 27342216 2017
Entrez Id: 248
Gene Symbol: ALPI
ALPI
0.010 Biomarker disease BEFREE Revised IAP 2015 growth charts diagnose more Indian children with overweight and obesity than CDC 2000 growth charts. 31353428 2019
Entrez Id: 250
Gene Symbol: ALPP
ALPP
0.010 Biomarker disease BEFREE Revised IAP 2015 growth charts diagnose more Indian children with overweight and obesity than CDC 2000 growth charts. 31353428 2019
Entrez Id: 51129
Gene Symbol: ANGPTL4
ANGPTL4
0.010 Biomarker disease BEFREE To evaluate the relationship between gestational weight gain (GWG) and circulating concentrations of ANGPTL4 in pregnant women with overweight and obesity, weight gain and fasting maternal blood samples of thirty-one pregnant women was drawn at 15, 24 and 32 weeks of gestation. 30127377 2018
Entrez Id: 55198
Gene Symbol: APPL2
APPL2
0.010 GeneticVariation disease BEFREE This study suggests that genetic variations in APPL2 are associated with overweight and obesity in Chinese population with normal glucose tolerance. 22462604 2012
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.010 GeneticVariation disease BEFREE The BDNF rs6265 variant may interact with overweight and obesity to influence obesity-related physical, metabolic and behavioural traits in Pakistani individuals. 30590963 2019
Entrez Id: 632
Gene Symbol: BGLAP
BGLAP
0.010 AlteredExpression disease BEFREE Association between TT genotype of TaqI polymorphism and low levels of OC was observed only in the population with overweight and obesity. 26323470 2015
Entrez Id: 55589
Gene Symbol: BMP2K
BMP2K
0.020 Biomarker disease BEFREE We randomized 130 younger, physically inactive women and men with overweight and obesity (body mass index: 25-35 kg m<sup>-</sup><sup>2</sup>) to 6 months of habitual lifestyle (control; CON, n=18), active commuting (BIKE, n=35) or leisure-time exercise of moderate (MOD, 50% VO<sub>2</sub>peak reserve, n=39) or vigorous intensity (VIG, 70% VO<sub>2</sub>peak reserve, n=38). 28993707 2018
Entrez Id: 55589
Gene Symbol: BMP2K
BMP2K
0.020 Biomarker disease BEFREE One hundred thirty physically inactive women and men (20-45 yr) with overweight and obesity were randomized to 6 mo of habitual lifestyle (CON, n = 18), active commuting (BIKE, n = 35), or leisure-time exercise of moderate [MOD, 50% peak oxygen uptake (V̇o<sub>2peak</sub>)-reserve, n = 39] or vigorous (VIG, 70% V̇o<sub>2peak</sub>-reserve, n = 38) intensity. 30605397 2019
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.010 GeneticVariation disease BEFREE Sex-stratified analyses indicated that overweight and obesity were associated with SBP (overweight: β = 6.77, P < 0.01; obese: β = 11.65, P < 0.001) and obesity was correlated with DBP (β = 9.86, P < 0.001) among males. 28633388 2017