Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2252
Gene Symbol: FGF7
FGF7
0.060 Biomarker disease BEFREE The recombinant human truncated Keratinocyte growth factor (Palifermin) is the only FDA approved medicine for the treatment of oral mucositis. 30999249 2019
Entrez Id: 2252
Gene Symbol: FGF7
FGF7
0.060 Biomarker disease BEFREE We are confident that KGF is beneficial in the prevention of oral mucositis in adults who are receiving: a) radiotherapy to the head and neck with cisplatin or fluorouracil; or b) chemotherapy alone for mixed solid and haematological cancers. 29181845 2017
Entrez Id: 2252
Gene Symbol: FGF7
FGF7
0.060 Biomarker disease BEFREE Specifically, KGF is currently being evaluated in clinical trials sponsored by Amgen (Thousand Oaks, CA) to test its ability to ameliorate severe oral mucositis (OM) that results from cancer chemoradiotherapy. 24188496 2014
Entrez Id: 2252
Gene Symbol: FGF7
FGF7
0.060 Biomarker disease BEFREE Prevention of radiation-induced oral mucositis after adenoviral vector-mediated transfer of the keratinocyte growth factor cDNA to mouse submandibular glands. 19584147 2009
Entrez Id: 2252
Gene Symbol: FGF7
FGF7
0.060 Biomarker disease BEFREE In 2005, palifermin [recombinant human keratinocyte growth factor (KGF)] was approved to decrease the incidence and duration of severe oral mucositis in patients with hematologic malignancies receiving myelotoxic therapy requiring hematopoietic stem cell support. 18708365 2008
Entrez Id: 2252
Gene Symbol: FGF7
FGF7
0.060 Biomarker disease BEFREE KGF is currently being evaluated in clinical trials to test its ability to ameliorate severe oral mucositis (OM) that results from cancer chemoradiotherapy. 15327889 2004