Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
0.040 Biomarker disease BEFREE In response to Mtb, peripheral blood mononuclear cells (PBMCs) from alcoholic young healthy individuals with latent tuberculosis infection (LTBI) produced significantly higher amounts of IFN-α than those from non-alcoholic young healthy LTBI+ individuals and alcoholic and non-alcoholic old healthy LTBI+ individuals. 30071107 2018
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
0.040 Biomarker disease BEFREE We conclude that increased cAMP inhibits IFN-g production through PKA type I pathway in tuberculosis infection. 29438524 2018
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
0.040 Biomarker disease BEFREE Numerous studies identify that IP-10 and IFN-<i>γ</i> are involved in leucocyte migration and activation and regarded as promising surrogate biomarkers in human and bovine tuberculosis infection, but there is lack of evidence for IP-10 in nonhuman primates. 28512637 2017
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
0.040 Biomarker disease BEFREE Together, our data support a model in which suppression of alternative macrophage activation by type I IFN during M. tuberculosis infection, in the absence of IFN-γ signaling, contributes to host protection. 27849167 2016