| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | disease | BEFREE | Pooled analyses showed that low miR-139 expression was related to worse overall survival (OS) [hazard ratio (HR) = 2.27; 95% confidence intervals (CI): 1.74-2.95; P < 0.001] in solid tumors, including hepatocellular carcinoma (HCC) and glioblastoma multiforme (GBM), consisting with the results of TCGA. | 30290990 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | The present study may thus form the basis for further exploration of hsa-miR-139-5p, not only as a therapeutic agent, but also as a diagnostic biomarker for GBM as well as a predictive marker for patient survival. | 31423264 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | miR-139-3p was remarkably down-expressed in glioblastoma tissue compared to control normal tissue. | 31173298 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | In summary, the results of this study verified that LINC01579 modulated cell proliferation and cell apoptosis in GBM by competitively binding with miR-139-5p to regulate EIF4G2, which provided a new clue to figure out potential therapy for patients suffered from GBM. | 31187495 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | A novel functional polymorphism of <i>GFAP</i> decrease glioblastoma susceptibility through inhibiting the binding of miR-139. | 29746255 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | MicroRNA-139-5p acts as a tumor suppressor by targeting ELTD1 and regulating cell cycle in glioblastoma multiforme. | 26449464 | 2015 | ||||
|
0.080 | Biomarker | disease | BEFREE | These results confirm that miR-139-5p suppresses GBM migration and invasion and highlight its potential as a biomarker and therapeutic target for treating GBM. | 25833697 | 2015 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Using computational and TCGA analysis, we identified miR-139 as being downregulated in glioblastoma in comparison with human brain tissue, as well as possessing a putative target site in Mcl-1 mRNA. | 23551751 | 2013 |