Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 468
Gene Symbol: ATF4
ATF4
0.030 AlteredExpression disease BEFREE Interestingly, high ATF4 expression was associated with poor overall survival suggesting involvement of PERK signaling in GBM progression. 31534165 2019
Entrez Id: 468
Gene Symbol: ATF4
ATF4
0.030 Biomarker disease BEFREE These findings suggest that ISR and ATF4 are involved in the death crosstalk between the endoplasmic reticulum and mitochondria and might be a potential target to enhance the therapeutic effect of temozolomide in patients with glioblastoma multiforme.Anat Rec, 2018. 29698579 2018
Entrez Id: 468
Gene Symbol: ATF4
ATF4
0.030 AlteredExpression disease BEFREE To investigate the significance of PERK, we studied activation of the PERK-eIF2α-ATF4 pathway in GBM after ionizing radiation (IR). 29991528 2018