Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4868
Gene Symbol: NPHS1
NPHS1 		0.330 GeneticVariation disease BEFREE Nineteen patients (53%), especially those with minimal change nephrotic syndrome (MCNS) at initial biopsy (p < 0.002), entered complete remission with CSA monotherapy, including one patient with compound heterozygous NPHS1 and dominant ACTN4 mutation, respectively. 25903641 2015
Entrez Id: 4868
Gene Symbol: NPHS1
NPHS1 		0.330 GeneticVariation disease BEFREE Patients with a single mutation in NPHS1 received a diagnosis before those with potentially nongenetic NS and had a good response to therapies.Renal function was normal in all cases. 19406966 2009
Entrez Id: 4868
Gene Symbol: NPHS1
NPHS1 		0.330 Biomarker disease CTD_human Decreased tyrosine phosphorylation of nephrin in rat and human nephrosis. 18256598 2008
Entrez Id: 4868
Gene Symbol: NPHS1
NPHS1 		0.330 GeneticVariation disease BEFREE The analysis of NPHS1 revealed no specific MCNS-associated mutation. 15086927 2004
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.100 GeneticVariation disease BEFREE Angiotensin-converting enzyme genotype is not a significant genetic risk factor for idiopathic nephrotic syndrome in Croatian children. 25997642 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.100 Biomarker disease BEFREE Association of ACE and MDR1 Gene Polymorphisms with Steroid Resistance in Children with Idiopathic Nephrotic Syndrome. 26154535 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.100 GeneticVariation disease BEFREE We analyzed the association of ACE gene I/D polymorphism with the clinical presentation of minimal change nephrotic syndrome (MCNS) in a Turkish child population. 22017506 2012
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.100 GeneticVariation disease BEFREE An assessment of the association between ACE I/D gene polymorphism and idiopathic nephrotic syndrome (INS) susceptibility in children is still controversial. 21946394 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.100 GeneticVariation disease BEFREE ACE I/D gene polymorphism can't predict the steroid responsiveness in Asian children with idiopathic nephrotic syndrome: a meta-analysis. 21611163 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.100 GeneticVariation disease BEFREE Effect of angiotensin-converting enzyme gene insertion/deletion polymorphism on steroid resistance in Egyptian children with idiopathic nephrotic syndrome. 20418353 2010
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.100 GeneticVariation disease BEFREE Angiotensin-converting enzyme gene polymorphism in children with idiopathic nephrotic syndrome. 16645262 2006
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.100 GeneticVariation disease BEFREE Angiotensin converting enzyme gene polymorphisms do not predict the course of idiopathic nephrotic syndrome in Swiss children. 17199794 2006
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.100 GeneticVariation disease BEFREE In the entire group of children with NS, the frequencies of the II, ID, and DD genotypes of ACE gene were 13.7%, 38.3% and 48%, respectively. 16208534 2005
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.100 GeneticVariation disease BEFREE Angiotensin-converting enzyme gene polymorphism in patients with minimal-change nephrotic syndrome and focal segmental glomerulosclerosis. 9434071 1997
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.050 GeneticVariation disease BEFREE A PRISMA-compliant meta-analysis of MDR1 polymorphisms and idiopathic nephrotic syndrome: Susceptibility and steroid responsiveness. 28614261 2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.050 GeneticVariation disease BEFREE Erratum: A PRISMA-compliant meta-analysis of MDR1 polymorphisms and idiopathic nephrotic syndrome: Susceptibility and steroid responsiveness: Erratum. 31305689 2017
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.050 GeneticVariation disease BEFREE Report of novel genetic variation in NPHS2 gene associated with idiopathic nephrotic syndrome in South Indian children. 26820844 2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.050 GeneticVariation disease BEFREE ABCB1 polymorphisms and steroid treatment in children with idiopathic nephrotic syndrome. 27719329 2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.050 GeneticVariation disease BEFREE Association of ACE and MDR1 Gene Polymorphisms with Steroid Resistance in Children with Idiopathic Nephrotic Syndrome. 26154535 2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.050 GeneticVariation disease BEFREE MDR1 polymorphisms and idiopathic nephrotic syndrome in Slovak children: preliminary results. 25559283 2015
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.050 GeneticVariation disease BEFREE Mutational analysis of the NPHS2 gene in Czech patients with idiopathic nephrotic syndrome. 22578956 2012
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.050 GeneticVariation disease BEFREE We reviewed the clinical features of 40 patients with NS associated with heterozygous mutations or variants in NPHS1 (n = 7) or NPHS2 (n = 33). 19406966 2009
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.050 GeneticVariation disease BEFREE NPHS2 (podicin) mutations in Turkish children with idiopathic nephrotic syndrome. 17899208 2007
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2 		0.050 GeneticVariation disease BEFREE Mapping a gene (SRN1) to chromosome 1q25-q31 in idiopathic nephrotic syndrome confirms a distinct entity of autosomal recessive nephrosis. 8589695 1995
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.040 AlteredExpression disease BEFREE Extensive workups were done, and there were elevated serum levels of interleukin-6 and vascular endothelial growth factor (VEGF), capillary pseudothrombus accumulation associated with minimal change nephrotic syndrome, CKD, and WM. 31531336 2019