Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.360 Biomarker disease BEFREE Intramucosal HDGC (pT1a) presents with an "indolent" phenotype, characterized by typical signet ring cells without immunoexpression of Ki-67 and p53, while advanced carcinomas (pT > 1) display an "aggressive" phenotype with pleomorphic cells, that are immunoreactive for Ki-67 and p53. 27573781 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.360 Biomarker disease CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.360 Biomarker disease CTD_human Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 22484628 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.360 AlteredExpression disease BEFREE Furthermore, AJCC stage and P53 expression dramatically affected the prognosis of FGC patients. 21400534 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.360 GeneticVariation disease BEFREE The present study was aimed at searching for germ line mutations of TP53 gene in familial gastric cancer with cluster for Li-Fraumeni syndrome or Li-Fraumeni-like syndrome. 19674071 2010
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.360 Biomarker disease BEFREE These results suggest that Ile31-type p53 may be partly involved in FGC because of its low transcriptional activity and low cell proliferation suppressing activity. 17690113 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.360 GeneticVariation disease BEFREE Our results suggest that TP53 mutational screening in FGC families should be interpreted with caution because additional TP53 mutation-carrying HDGC families may also show LFS-related phenotypes. 15368100 2004
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.360 Biomarker disease BEFREE Absence of microsatellite instability and germline mutations of E-cadherin, APC and p53 genes in Japanese familial gastric cancer. 11399952 2001