Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.360 | Biomarker | disease | BEFREE | Intramucosal HDGC (pT1a) presents with an "indolent" phenotype, characterized by typical signet ring cells without immunoexpression of Ki-67 and p53, while advanced carcinomas (pT > 1) display an "aggressive" phenotype with pleomorphic cells, that are immunoreactive for Ki-67 and p53. | 27573781 | 2017 | ||||
|
0.360 | Biomarker | disease | CTD_human | Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. | 24816253 | 2014 | ||||
|
0.360 | Biomarker | disease | CTD_human | Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. | 22484628 | 2012 | ||||
|
0.360 | AlteredExpression | disease | BEFREE | Furthermore, AJCC stage and P53 expression dramatically affected the prognosis of FGC patients. | 21400534 | 2011 | ||||
|
0.360 | GeneticVariation | disease | BEFREE | The present study was aimed at searching for germ line mutations of TP53 gene in familial gastric cancer with cluster for Li-Fraumeni syndrome or Li-Fraumeni-like syndrome. | 19674071 | 2010 | ||||
|
0.360 | Biomarker | disease | BEFREE | These results suggest that Ile31-type p53 may be partly involved in FGC because of its low transcriptional activity and low cell proliferation suppressing activity. | 17690113 | 2007 | ||||
|
0.360 | GeneticVariation | disease | BEFREE | Our results suggest that TP53 mutational screening in FGC families should be interpreted with caution because additional TP53 mutation-carrying HDGC families may also show LFS-related phenotypes. | 15368100 | 2004 | ||||
|
0.360 | Biomarker | disease | BEFREE | Absence of microsatellite instability and germline mutations of E-cadherin, APC and p53 genes in Japanese familial gastric cancer. | 11399952 | 2001 |