Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.030 Biomarker disease BEFREE Here, we reported that nutlin-3 plus tanshinone IIA significantly potentiated the cytotoxic and apoptotic induction effects of imatinib by down-regulation of the AKT/mTOR pathway and reactivating the p53 pathway deeply in Ph+ ALL cell line. 29046392 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.030 GeneticVariation disease BEFREE One patient with lymphoid BC/Ph+ ALL who harbored a T315I ABL mutation and was treated with ponatinib was found to have developed a newly acquired V216M TP53 mutation (12% of transcripts) when becoming resistant to ponatinib. 25894969 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.030 AlteredExpression disease BEFREE Northern-blot analysis of the p53 gene showed that one case of CD7(+) ALL had altered p53 mRNA. 1359196 1992