Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.200 Therapeutic disease RGD Mechanisms of prostate atrophy after LHRH antagonist cetrorelix injection: an experimental study in a rat model of benign prostatic hyperplasia. 22684563 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.010 GeneticVariation disease BEFREE Microdissected DNA selectively extracted from paraffin-embedded sections of 29 cases of PCA and 1 benign prostatic hypertrophy were analyzed for p53 mutation by single-strand conformation polymorphism (SSCP) of polymerase chain reaction (PCR)-amplified DNA fragments followed by direct sequencing. 9800953 1998
Entrez Id: 54360
Gene Symbol: CYTL1
CYTL1
0.010 Biomarker disease BEFREE More recently, studies have also potentially linked Cytl1 with a variety of conditions including cardiac fibrosis, smoking, alcohol dependence risk, and tumours such as benign prostatic hypertrophy, lung squamous cell carcinoma, neuroblastoma and familial colorectal cancer. 31089746 2019
Entrez Id: 3964
Gene Symbol: LGALS8
LGALS8
0.010 AlteredExpression disease BEFREE Primer pairs within the 3' untranslated region of PCTA-1 and reverse transcription-PCR demonstrate selective expression of PCTA-1 by prostate carcinomas versus normal prostate and benign prostatic hypertrophy. 8692978 1996
Entrez Id: 5617
Gene Symbol: PRL
PRL
0.300 Biomarker disease CTD_human Promoting action of prolactin released from a grafted transplantable pituitary tumor (MtT/F84) on rat prostate carcinogenesis. 2208075 1990
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
0.200 Therapeutic disease RGD Protective effect of γ-tocopherol-enriched diet on N-methyl-N-nitrosourea-induced epithelial dysplasia in rat ventral prostate. 24205794 2013
Entrez Id: 1915
Gene Symbol: EEF1A1
EEF1A1
0.030 AlteredExpression disease BEFREE Rapid expression cloning and differential RNA display identifies a gene, named prostate tumor inducing gene-1 (PTI-1), that is differentially expressed in prostate cancer versus normal prostate and benign prostatic hypertrophy. 8988032 1997
Entrez Id: 2252
Gene Symbol: FGF7
FGF7
0.300 Biomarker disease CTD_human Relationship between upregulated oestrogen receptors and expression of growth factors in cultured, human, prostatic stromal cells exposed to estradiol or dihydrotestosterone. 14999240 2004
Entrez Id: 8772
Gene Symbol: FADD
FADD
0.200 Therapeutic disease RGD Rice Hull Extract Suppresses Benign Prostate Hyperplasia by Decreasing Inflammation and Regulating Cell Proliferation in Rats. 27441629 2016
Entrez Id: 367
Gene Symbol: AR
AR
0.220 Biomarker disease BEFREE The androgen receptor plays different roles in macrophage-induced proliferation in prostate stromal cells between transitional and peripheral zones of benign prostatic hypertrophy. 28694768 2017
Entrez Id: 58191
Gene Symbol: CXCL16
CXCL16
0.010 AlteredExpression disease BEFREE The expression of CXCL16/CXCR6 was significantly higher in prostate cancer than in benign prostatic hypertrophy. 21468586 2011
Entrez Id: 10663
Gene Symbol: CXCR6
CXCR6
0.010 AlteredExpression disease BEFREE The expression of CXCL16/CXCR6 was significantly higher in prostate cancer than in benign prostatic hypertrophy. 21468586 2011
Entrez Id: 966
Gene Symbol: CD59
CD59
0.010 AlteredExpression disease BEFREE The present study investigated the expression and function of CD59 on human prostatic tumor cells in situ and on 5 human prostate cell lines in vitro originating from either metastatic tumors or benign prostate hypertrophy epithelial cells. 9185710 1997
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.010 GeneticVariation disease BEFREE The results indicated that discontinuation of tamsulosin for one month largely reduces the manifestations of intraoperative floppy iris syndrome in rats, which may suggest to change preoperative treatment for benign prostatic hypertrophy with another class of drugs that do not interact with the iris receptors. 30651774 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.010 AlteredExpression disease BEFREE Using a monoclonal antibody (TA1) directed against human Her-2/neu oncogene product and an immunohistochemical staining method, no Her-2/neu expression was noted with benign prostatic hypertrophy (15 samples). 7685420 1993
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.010 AlteredExpression disease BEFREE We detected high levels of IL-8 in sera from patients with CaP compared with healthy controls and patients with benign prostatic hypertrophy. 27159450 2016
Entrez Id: 177
Gene Symbol: AGER
AGER
0.010 AlteredExpression disease BEFREE We investigated RAGE and amphoterin mRNA expression in prostate cancer cell lines (DU145, PC-3, and LNCaP cells), hormone-refractory prostate cancer tissues, and paired untreated primary prostate cancer and normal prostate (including benign prostatic hypertrophy (BPH)) tissues using real-time quantitative PCR. 15666359 2005
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
0.010 AlteredExpression disease BEFREE We investigated RAGE and amphoterin mRNA expression in prostate cancer cell lines (DU145, PC-3, and LNCaP cells), hormone-refractory prostate cancer tissues, and paired untreated primary prostate cancer and normal prostate (including benign prostatic hypertrophy (BPH)) tissues using real-time quantitative PCR. 15666359 2005
Entrez Id: 3791
Gene Symbol: KDR
KDR
0.200 Biomarker disease RGD [Angiogenesis and regulatory factors in rats with BPH induced by testosterone]. 15999482 2005