In addition, five potential altered microRNA-mRNA interactions were found, including hsa-miR-939-5p-<i>PLXNA4</i>, hsa-miR-3918-<i>CTIF</i>, hsa-miR-4768-5p-<i>PDE5A</i>, hsa-miR-1273g-3p-<i>VPS53</i>, and hsa-miR-1972-<i>PCSK9.</i> In summary, differentially expressed genes and microRNAs in response to EGCG treatment in IPF fibroblasts were identified in the current study.